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Children aged 9 to 14 years can now receive the human papillomavirus (HPV) vaccine on a two-dose schedule, rather than a three-dose one, according to updated recommendations issued by the Centers for Disease Control and Prevention (CDC). The recommendations are based on the findings of a year-long review of new clinical trial data conducted by the Advisory Committee on Immunization Practices (ACIP). The data show that among girls and boys in this age range, immunogenicity associated with the two-dose regimen was not inferior to, and in some cases was superior to, that seen with the three-dose regimen.
Medscape, December 15, 2016
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