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October 16, 2023

U-M RNA Innovation Seminars Series

“Bacterial Small RNAs: Regulatory Circuits, On & Off Switches, & Quality Control”


Susan Gottesman, Ph.D.

Chief, Laboratory of Molecular Biology

Head Biochemical Genetics Section

NIH/NCI


Monday, October 23, 4:00 PM - 5:00 PM ET

BSRB ABC Seminar Rooms, Hybrid Link

Affiliated Seminars

Harvard Medical School Initiative for RNA Medicine (HIRM)


Speaker Carmelo Nucera, MD, PhD, “Identification of a new lincRNA in the thyroid gland”


Speaker Amanda Whipple, PhD, "Regulation of imprinted gene expression in the brain"


Moderator: Frank Slack, PhD


October 25, 2023, 4 PM ET  Zoom Registration

“Systems Biology Tools for Drug Discovery and Metabolic Modeling”


Presented by:

Sriram Chandrasekaran, Ph.D.

 

Today! Monday, October 16

11:00 AM – 12:00 PM EST

BSRB - 1020 Kahn Auditorium

 

Hosted by:

Sundeep Kalantry, Ph.D.

CRB Faculty Member

“Gene Therapy for Brain Tumors: from brain/immune co-evolution to a novel therapy in humans”

 

Presented by: 

Pedro Lowenstein, M.D., Ph.D. 

CRB Faculty Member

 

Monday, October 23

11:00 AM – 12:00 PM EST

BSRB - 1020 Kahn Auditorium

 

Hosted by: 

Jordan Shavit, M.D., Ph.D.

'miR-214 as coordinator of tumor-stroma crosstalk during cancer progression and as therapeutic target'


Daniela Taverna, Ph.D.

Full Professor of Molecular Biology

University of Torino, Italy


Tuesday, Oct. 24, 2023 at 3:00 PM EST

Join Virtually Register Here

Oral Defenses

U-M Oral Dissertations

On the Evolution of Sperm Morphology and Sperm-Related Genes in a Howler Monkey Hybrid System


Molly Hirst, Ecology & Evolutionary Biology

Advisors: Liliana Cortes-Ortiz and Trisha Wittkopp


Wednesday, 18 October 9AM

BIOLOGICAL SCIENCES BUILDING ROOM 1010

Kinesin Regulation via Kinesin Binding Protein (KIFBP) And Autoinhibition


Zhenyu Tan, Biophysics

Advisor: Michael Cianfrocco, Ph.D.


Wednesday, October 18

10:00 AM

RACKHAM GRADUATE SCHOOL, EARL LEWIS ROOM

For more information and to view the full schedule of upcoming U-M Oral Defenses, please visit the Rackham Graduate School Oral Defenses website.

RNA SOCIETY

News

The RNA Society has once again entered into an agreement with Lexogen for continued support of the RNA Salon program including the option to receive 2 years of RNA Salon funding.

 

With this agreement in place, we have now opened the application system and invite RNA Salon applications for 2023/24. High-quality applications will once again be chosen for two years of funding.

 

You will find details regarding the application guidelines and the link to the application system on the RNA Society website: https://www.rnasociety.org/salons

 

Applications will be accepted until October 20, 2023. If you cannot meet this timeline due to exceptional circumstances, or for more information, please contact Ute Kothe, RNA Salon Program Coordinator, at Ute.Kothe@umanitoba.ca

Lexogen RNA Expertise Blog Series

RNA Sequencing in Drug Discovery and Development


October 10 Blog Post by Lexogen

In the News

Michigan Medicine Health Lab features CRB faculty work with biomarkers

CRB Faculty Members Sunitha Nagrath, Ph.D., and Muneesh Tewari, Ph.D., M.D., and are learning the potential that liquid biopsies hold as a potential non-invasive, diagnostic tool. Their research is cited in a new article recently published in Health Lab.


Dr. Nagrath reveals that circulating biomarkers found in bodily fluids such as blood, hold a host of undiscovered possibilities, and suggests they might even become part of a routine blood test down the road.

Dr. Tawari discovered that RNA was also found in the blood as a circulating marker - perhaps opening up yet another promising new path for RNA therapeutics development.


Read the full story in Michigan Medicine Health Lab.

Tomorrow! UM Tissue Barriers iPSC Meeting at Kellogg Eye Center

Rajesh C. Rao, M.D., Center for RNA Biomedicine Faculty Member, will be presenting a talk at the UM Tissue Barriers iPSC Meeting


"Stem Cell Therapy: Can We Repair the Barrier?"


October 17, 2023 | 1:20-2:10 PM | Kellogg Eye Center


Stem Cells: iPSC Modeling Meeting flyer.

Meetings

Nature Conferences

Cracking The Code: The Dawn of Nucleic Acids - October 17-19, 2023

Register Here

In-person Nature Conference at Worcester Polytechnic Institute, Worcester, MA.


The conference will discuss the development of nucleic acid medicines — both the recent clinical successes, and current and upcoming challenges. By bringing together academics in basic and translational research and their peers in thriving biotechnology companies and promising start-ups, the conference aims to foster dialog and to spearhead collaborations. 

Midwest Symposium for Oligonucleotide Therapeutics - November 12-13

Free Registration (virtual, in-person)

Eli Lilly is sponsoring a Midwest Symposium for Oligonucleotide Therapeutics (Nov 12-13) at the Hilton Indianapolis Hotel and Suites. Registration is free and it is a great opportunity for students (and PIs) to network, learn about RNA therapeutics from leading experts in the field, and share their work on RNA biology, oligonucleotide chemistry, RNA/DNA editing, and/or oligonucleotide delivery.

 

We have an exciting line up of keynote and invited speakers committed to present at the symposium. These include Stanley Crooke (Ionis, n-Lorem Foundation), Ron Weiss (MIT), Sudhir Agrawal (University of Massachusetts, ARNAY Sciences), Thomas Gaj (University of Illinois), and Craig Duvall (Vanderbilt University). Register at the link above.

16th Annual BIDMC Cancer Center Symposium - November 17, 2023

Targeted and Immune – Based Cancer Therapy

Register Here

On behalf of the Cancer Center at BIDMC, we invite you to join us for the 16th Annual BIDMC Cancer Center Symposium which will be held in-person at the Joseph B. Martin Conference Center.

 

The symposium will provide updates and presentations from some of the most renowned physicians in the field of cancer research and targeted immune based therapies.

Joint Keystone Symposia on RNA Modifications / Regulatory RNAs

December 12-16, 2023 in Banff, AB, Canada

Keystone Symposia Meetings:

RNA Modifications in Health and Disease and Regulatory RNAs: Emerging Mechanisms 


For more information and to register, visit: Keystone Symposia

Our members' publications are available through Altmetric. Queries are currently available: CRISPR, microRNA, molecule, RNA, RNA therapeutics, transcriptome, and translation.


Below are recent highlights.

Elzinga SE, Eid SA, McGregor BA, Jang DG, Hinder LM, Dauch JR, Hayes JM, Zhang H, Guo K, Pennathur S, Kretzler M, Brosius FC, Koubek EJ, Feldman EL, Hur J. Transcriptomic analysis of diabetic kidney disease and neuropathy in mouse models of type 1 and type 2 diabetes. Dis Model Mech. 2023 Oct 1;16(10):dmm050080. doi: 10.1242/dmm.050080. Epub 2023 Oct 4. PMID: 37791586. https://doi.org/10.1242/dmm.050080

Roggenbuck J, Eubank BHF, Wright J, Harms MB, Kolb SJ; ALS Genetic Testing and Counseling Guidelines Expert Panel. Evidence-based consensus guidelines for ALS genetic testing and counseling. Ann Clin Transl Neurol. 2023 Sep 10. doi: 10.1002/acn3.51895. Epub ahead of print. PMID: 37691292. https://doi.org/10.1002/acn3.51895

Perelman RT, Schmidt A, Khan U, Walter NG. Spontaneous Confinement of mRNA Molecules at Biomolecular Condensate Boundaries. Cells. 2023 Sep 11;12(18):2250. doi: 10.3390/cells12182250. PMID: 37759470; PMCID: PMC10526803. https://doi.org/10.3390/cells12182250

Harrison KR, Snead D, Kilts A, Ammerman ML, Wigginton KR. The Protective Effect of Virus Capsids on RNA and DNA Virus Genomes in Wastewater. Environ Sci Technol. 2023 Sep 1. doi: 10.1021/acs.est.3c03814. Epub ahead of print. PMID: 37656816. DOI: https://doi.org/10.1021/acs.est.3c03814

Job Postings

Postdoctoral Fellow UMich Department of Pathology


The laboratory of Dr. Sethu Pitchiaya, Assistant Professor, Department of Urology, Department of Pathology at the University of Michigan seeks to hire an enthusiastic Postdoctoral fellow to work on exciting projects related to mammalian stress response mechanisms. Learn more.

University of Michigan BIBC Tenure Track Faculty Search


The University of Michigan has launched a Tenure Track Faculty Search for the BioInnovations in Brain Cancer Initiative (BIBC), led by Center for RNA Biomedicine Faculty Member Dr. Maria G. Castro and Dr. Steven Schwendeman. Learn more.

The University of Michigan Single Cell Spatial Analysis Program is hiring for Faculty Positions


Intellectual foundation and research resources to enhance single-cell and spatial analyses. Learn more.

RNA Biology Laboratory at the National Cancer Institute - Biologists



Part of NIH in Frederick, MD, is currently seeking to recruit outstanding RNA biologists. Learn more.

The University of California Irvine (UCI), Department of Ophthalmology

Full-Time Position


Inviting applicants focused on the development of genetic engineering and genome editing technologies. Learn more.

Postdoctoral Research Fellow and Graduate Research Assistants

Dr. Guizhi (Julian) Zhu Lab | University of Michigan


Multiple full-time openings for Postdoctoral Research Fellow and Graduate Research Assistants. Learn more.

Research Technician and Post-Doctoral Research Fellow | Fred Hutchinson Cancer Center | The Lapointe Lab


Seeking to fill two positions: Research Technician and Post-Doctoral Research Fellow. Learn more.

Research Technician - Yadavalli Lab



Seeking full-time technician or research scientist to perform cutting-edge research in RNA biology using high-throughput sequencing methods. Learn more.

Postdoctoral Position - Maquat Lab


A postdoctoral position is open. Applicants should hold a PhD or MD/PhD degree(s) and have expertise in molecular, cellular, or structural biology. Learn more.

Postdoctoral Position - Cooperman Laboratory


Seeking postdoctoral student with a strong interest in understanding the mechanism and regulation of cytoplasmic eukaryotic protein synthesis. Learn more.

Volunteer - RNA Society


Seeking to fill the position of RNA Salon Program Coordinator and invites current Full members interested in leading this program to come forward. Learn more.

For complete details on current openings and how to apply for these positions, visit the Recruitment Opportunities page on our website.

Recruitment Opportunities

Save the Date

2024 RNA Symposium | March 8, 2024

Unmasking the Power of RNA: From Structure to Medicine

The 8th annual symposium will take place on Friday, March 8, 8:30 a.m. - 4:00 p.m. in the A. Alfred Taubman Biomedical Science Research Bldg., Kahn Auditorium at 109 Zina Pitcher Place in Ann Arbor, Michigan.


Speakers: Drew Weissman, M.D., Ph.D., University of Pennsylvania, 2023 Nobel laureate for Physiology or Medicine for his work on mRNA vaccines; Victoria D'Souza, Ph.D., Harvard University; Brenton R. Graveley, Ph.D., University of Connecticut; Leemor Joshua-Tor, Ph.D., Cold Spring Harbor Laboratory; and Peter Todd, M.D., Ph.D., University of Michigan

To share your news and comments, please contact

rna-communications@umich.edu

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