Announcement for Summer 2024 | | |
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The RNA Transcript will be published monthly during Summer 2024. Keep an eye on your inbox for the June, July, and August issues.
Don't forget, you can access recent news, past editions of The RNA Transcript, as well as RNA Translated 2024, the latest issue of our annual magazine and report, on our website anytime to add to your summer reading list!
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U-M RNA Innovation Seminar Series | Monday, June 3, 4 p.m. | |
Multidisciplinary Team Secures $3 Million Grant to Advance RNA-Based Treatments for Rare Cystic Fibrosis Mutations | |
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A multidisciplinary team of center members has secured a $3 million grant from the Cystic Fibrosis Foundation.
Under the leadership of RNA Therapeutics Director Michelle Hastings, Ph.D., and colleagues Rachel Niederer, Ph.D., and Alexandra Piotrowski-Daspit, Ph.D., the funding will further research into novel RNA-based treatments for rare cystic fibrosis mutations that currently have no targeted therapies. Each member will oversee a different link in the bench-to-bedside chain.
Read this informative article by Paul Avedisian and Michele Santillan to learn more about how this dynamic team of researchers is leveraging their strengths and collective wealth of knowledge on the CTFR gene to revolutionize treatment options for those suffering from rare and often untreatable forms of cystic fibrosis.
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Solving science's greatest mysteries:
Mason Myers from Scooby-Doo to CRISPR superhero
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In this issue, we’re reintroducing the popular “RNA Featured Researcher” section of the website, to provide a snapshot of the people that make up the diverse, wide-ranging RNA research community at the U-M. Each installment showcases a faculty or student member, who is asked questions about their background, areas of research, recent accomplishments, and hopes for the future — with a few off-the-cuff tidbits thrown into the mix. We hope you enjoy the return of this column, and let us know what you think! | |
Mapping the way to personalized kidney treatments: NEPTUNE's innovative approach | |
Learn all about Dr. Ljungman's KLIPP technique for CRISPR-Cas 9 systems | |
Enjoy this video which details KLIPP, a "split enzyme" system pioneered by Center for RNA Biomedicine co-director, Mats Ljungman, Ph.D., whose lab has done dynamic work putting together a strong proof of concept for this promising RNA-based therapy. | | |
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"Statistical methods for genetics data"
Oral defense by Boran Gao | Biostatistics
Advisor: Xiang Zhou, Ph.D.
Wednesday, June 6 | 10 a.m.
M4034, School of Public Health II
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6th Annual RNATx: From Concept to Clinic | June 26 – 28, 2024 | |
GRC on Post-transcriptional Gene Regulation | July 14 – 19, 2024 | | |
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This milestone event promises to be extraordinary, with over 100 speakers, at least half of whom will be selected from submitted abstracts, ensuring a diverse and inclusive representation of leaders in the field.
As we celebrate 25 years of friendship, collaboration, and networking, This gathering marks the inauguration of RNA Canada, a new initiative aimed at strengthening the bonds between the international RNA community and our Canadian colleagues.
Download the complete program.
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ncRNA World 2024 | October 7 – 9, 2024 | | |
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Join us in Basel in October to learn about the latest developments in Non-Coding RNA research. Mingle with the world-leading invited speakers during ample networking opportunities. Present your research at poster sessions and numerous selected oral presentations. Discover the beautiful medieval city of Basel.
Click here for more information and details on abstract submissions.
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EMBO Workshop: Spatial Omics | October 23 – 24, 2024 | | |
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Our members' publications are available through Altmetric.
Queries currently available:
CRISPR, microRNA, molecule, RNA, RNA therapeutics, transcriptome, and translation.
Below are recent highlights.
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Roh JD, Castro C, Yu A, Rana S, Shahul S, Gray KJ, Honigberg MC, Ricke-Hoch M, Iwamoto Y, Yeri A, Kitchen R, Guerra JB, Hobson R, Chaudhari V, Chang B, Sarma A, Lerchenmüller C, Al Sayed ZR, Diaz Verdugo C, Xia P, Skarbianskis N, Zeisel A, Bauersachs J, Kirkland JL, Karumanchi SA, Gorcsan J 3rd, Sugahara M, Damp J, Hanley-Yanez K, Ellinor PT, Arany Z, McNamara DM; IPAC Investigators; Hilfiker-Kleiner D, Rosenzweig A. Placental senescence pathophysiology is shared between peripartum cardiomyopathy and preeclampsia in mouse and human. Sci Transl Med. 2024 Apr 17;16(743):eadi0077. doi: 10.1126/scitranslmed.adi0077. Epub 2024 Apr 17. PMID: 38630848. | |
Narayan, Vikram M.; Eyrich, Nicholas; Huang, Eugene; Zheng, Yingye; Wei, John; Sokoll, Lori; Chan, Daniel; Patil, Dattatraya; Chinnaiyan, Arul; Tomlins, Scott A.; Lotan, Yair; Lin, Daniel; Scherr, Douglas; Kibel, Adam; Taneja, Samir S.; Bidair, Mohamed; Thompson, Ian M.; Sanda, Martin G. MP41-02 Combining serum prostate index with urinary PCA3 and TMPRSS2:ERG RNA testing improves detection of clinically-significant prostate cancer, Journal of Urology: May 2024 - Volume 211 - Issue 5S. doi: 10.1097/01.JU.0001008896.93851.5b.02. | |
Torrez RM, Nagaraja S, Menon A, Chang L, Ohi MD, Garner AL. Comparative Biochemical Studies of Disease-Associated Human Dicer Mutations on Processing of a Pre-microRNA and snoRNA. Biochemistry. 2023 Jun 6;62(11):1725-1734. doi: 10.1021/acs.biochem.2c00687. Epub 2023 May 2. PMID: 37130292. | |
Yang Y, Feng H, Tang Y, Wang Z, Qiu P, Huang X, Chang L, Zhang J, Chen YE, Mizrak D, Yang B. Bioengineered vascular grafts with a pathogenic TGFBR1 variant model aneurysm formation in vivo and reveal underlying collagen defects. Sci Transl Med. 2024 May 8;16(746):eadg6298. doi: 10.1126/scitranslmed.adg6298. Epub 2024 May 8. PMID: 38718134. | | |
For complete details on current openings and how to apply for these positions, visit the Recruitment Opportunities page on our website | | | | |
