Welcome Message

From Julie Zissimopoulos

CEASES ADRD affiliates are conducting research that is broadening our understanding of biomarkers for ADRD. We have included a selection of recently published studies and their findings in this Newsletter.

We would also like to call your attention to a public meeting next month hosted by the National Academies of Sciences, Engineering and Medicine to inform a study that will recommend research priorities for preventing and treating Alzheimer’s Disease and Related Dementias. Please consider joining to contribute your expertise. More information will be available on the NASEM website in the coming weeks. 

For more information, please visit our website or reach out to me at zissimop@usc.edu or our Program Administrator, Johanna Thunell, at jthunell@usc.edu.

Thirty-two social scientists from across the US learned about the biomedical and clinical foundations of AD/ADRD from leading experts at the Science of AD/ADRD for Social Scientists Program

CeASES ADRD hosted our third annual event, Science of AD/ADRD for Social Scientists, in March 2024 at USC. The program featured presentations by seven biomedical and clinical experts: Drs. Paul Aisen, David Bennett, Helena Chui, Sean Curran, Neda Jahanshad, Jessica Langbaum, and David Reuben. The speakers provided talks on the latest research across a range of topics, such as neuroscience, genetics, imaging, diagnostics, treatment and clinical care. Drs. Maria Corrada-Bravo and Jennifer Manly provided keynote addresses on dementia in the oldest old and pathways to brain health equity, respectively. Drs. Jennifer Ailshire, Eileen Crimmins, and Julie Zissimopoulos provided talks that featured social science studies grounded in findings from the basic sciences. Drs. Priscilla Novak and Stefania Forner, representatives from NIA and Alzheimer’s Association, respectively, provided information on opportunities. Thirty-two social scientists at all career stages from fields of economics, sociology, gerontology and public policy and from across 16 institutions attended. For more information on the event, please visit the website.

Call for papers in Alzheimer's & Dementia Special Issue: Advancing Dementia Care and Caregiving Science in ADRD

Alzheimer’s & Dementia is delighted to announce a Call for Papers for a Special Issue of Alzheimer’s & Dementia dedicated to advancing the science of Alzheimer’s disease and related dementias (AD/ADRD) care and caregiving and reflecting the multifaceted and pressing challenges within this domain.

The Special Issue is a follow-up to the 2023 National Research Summit on Care, Services, and Supports for Persons Living with Dementia and Their Care Partners/Caregivers, which convened for three virtual sessions on March 20-22, 2023 to review scientific progress, highlight innovative and promising approaches, and identify unmet research needs. The Special Issue aims to encapsulate the diverse spectrum of topics discussed during the summit, reflecting the multifaceted and pressing challenges within this domain. 

Please send an email to Haley Garland (hgarland@usc.edu) with your submission inquiries if you plan to submit to the Special Issue and include the topic area or theme.

The deadline for paper submissions is October 1, 2024, and the publication is expected in Spring 2025. For more information, please visit the A&D website.

CeASES ADRD collaborated with NIA-funded centers to host several workshops

Assessing Aging in Under-represented and Diverse Populations Webinar Series

CAPS, UT Austin, and CeASES ADRD co-hosted a two-part workshop series, each with over 100 participants. The first workshop, a hybrid event titled Ecological Momentary Assessments in Underrepresented Populations, featured research by Drs. Jason Hassenstab, Raenne Moore, and Nelson Roque using ecological momentary assessments (EMAs) with a particular focus on cognitive assessments. The webinar recording can be found here. The second virtual workshop, Challenges of Measuring and Assessing Cognitive Health in Diverse Populations, included 3 sessions: Cognitive Health Measurements Advancements and Challenges, Considerations for Evaluating Cognitive Health Across the Life Course in Diverse Populations, and Advancements in Cognitive Health Research. The recording for this webinar is accessible here.

Contextual Data Resources for Understanding the Role of the Exposome in Aging

On March 11-12, 2024, the USC/UCLA Center on Biodemography and Population Health hosted a hybrid workshop at the University of Southern California. With 65 attendees in person and virtually, the event focused on utilizing contextual data linked to aging surveys to understand the exposome's relationship with cognition, dementia (ADRD), and biological aging indicators. Presentations covered topics such as physical and social environment data, historical data analysis, best practices in using Contextual Data Resources (CDR), and approaches to constructing CDR data measures.

CeASES ADRD affiliates' research was featured in blog posts and conferences, including PAA

CeASES affiliates and fellows from the USC Schaeffer Center for Health Policy & Economics delve into the disparities in care, diagnosis, and outcomes for those living with dementia under Medicare Advantage (MA) versus Traditional Medicare (TM) in our new blog, "Does Medicare Advantage Provide Superior Care for Individuals with Dementia?"

Read More

CeASES ADRD Representation at PAA 2024

CeASES ADRD leadership and pilot PIs were active participants at this year's Population Association of America (PAA) annual meeting. Research by Dr. Chandra Muller (pilot PI) and colleagues was featured in a poster session. The study, The Effects of HBCU Attendance Among Black College-Goers on Later Life Physical Health, Mental Health, Cognitive Functioning, and Mortality, used High School and Beyond data to examine differences in outcomes of Black alumni of HBCU compared to Black alumni of non-HCB, finding no difference in their health or cognitive functioning.

The full list of PAA sessions featuring CeASES leadership and pilots can be found here.

Selected publications from CeASES ADRD affiliates on biomarkers, aging, and dementia

Eileen Crimmins and co-authors discuss how biomarker data can help improve our understanding of health changes in individuals and the causal pathways related to health in Dried blood spot based biomarkers in the Health and Retirement Study: 2006 to 2016.

Yuan Zhang and co-authors find biomarkers associated with aging are already evident among young adults in their 30s and attention should focus on age-related disease risk earlier in the life course in Sociodemographic patterns in biomarkers of aging in the Add Health cohort.

Matteo Farina and Jennifer Ailshire find perceived status among undocumented foreign born Hispanic/Latino adults was associated with lower scores on cognitive tasks sensitive to stress, age related decline and neurological impairments in Perceived social status modifies associations of plasma Alzheimer’s disease biomarkers on cognitive performance among Foreign Born Hispanic/Latinos.

Jennifer Manly and co-authors find elevated levels of AD biomarker p-tau181/Aβ42, by itself or combined with a low Aβ42/Aβ40 level, predicts clinically diagnosed AD in Risk of Alzheimer's disease is associated with longitudinal changes in plasma biomarkers in the multi-ethnic Washington Heights-Hamilton Heights-Inwood Columbia Aging Project (WHICAP) cohort.

Join our Network of over 275 social scientists from 85 institutions

Contact: Julie Zissimopoulos, PhD, Director, zissimop@usc.edu

Johanna Thunell, PhD, Program Administrator, jthunell@usc.edu

Julie Zissimopoulos, PhD, PI, USC

Dana Goldman, PhD, PI, USC

Mark Hayward, PhD, PI, UT Austin

Jay Bhattacharya, MD, PhD PI, Stanford

Eileen Crimmins, PhD, Core Director, USC

Jennifer Ailshire, PhD, Core Director, USC

Pinchas Cohen, MD, Advisory, USC

Jennifer Manly, PhD, Advisory, Columbia

Hector Gonzalez, PhD, Advisory, UCSD

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