Resveratrol preserves neuromuscular synapses, muscle fibers in aging mice - Science Daily, 3/7/17 - "resveratrol, a compound in the skin of red grapes and red wine, and metformin, a drug often prescribed to fight type 2 diabetes, have many of the neuroprotective benefits of a low-calorie diet and exercise ... resveratrol preserves muscle fibers as we age and helps protect connections between neurons called synapses from the negative effects of aging ... the diabetes drug metformin slowed the rate of muscle fiber aging, but it did not significantly affect aging of neuromuscular junctions. However, the drug may possibly protect synapses in different dosage amounts ... Metformin is an FDA-approved drug to treat diabetes, but our study hints it may also serve the purpose of slowing the motor dysfunction that occurs with aging ... In wine, resveratrol is in such small amounts you could not drink enough of it in your life to have the benefits we found in mice given resveratrol" - See resveratrol at Amazon.com and metformin at IAS.