Dear Colleague,
The California Initiative to Advance Precision Medicine (CIAPM) welcomed Spring with a multitude of engagement activities and resource development for the program. In this newsletter, we highlight a special interview following the career of a CIAPM-funded trainee-to-researcher studying Adverse Childhood Experiences, provide new web resources for Representative Research, request nominations for the California Precision Medicine Advisory Board, and announce the date in June for the CIAPM Advisory Council.
We look forward to seeing you at upcoming meetings.
The CIAPM Team
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Nominations for the CA Precision Medicine Advisory Board
We invite members of the public to submit nominations for a new member of the Advisory Council. The Newsom Administration created the California Precision Medicine Advisory Council to provide high-level guidance to the Governor’s Office of Planning and Research on matters relating to CIAPM. Members are California-based experts in precision medicine and represent patient advocacy and community groups, academia, private industry, health policy, clinical providers, venture capital, and philanthropy.
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Debuting a New Public Resource to Guide More Equitable Research
The Representative Research Collaborative added a new resource to the CIAPM Website, providing guidance for community members and researchers on how to more equitably recruit, educate, and obtain consent from diverse populations of participants in clinical trials. These educational resources are available on the Equitable Consent Frameworks & Guidance Webpage.
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Example Screenshot of New Web Resources on Clinical Trial Participation and Recruitment Tools
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Building and Expanding the CIAPM Network
Staff were well represented at meetings this spring, proactively reaching out to new communities and expanding our network within and beyond California.
- Biocom California, the state’s largest biotech trade association, featured Director McCall with a fireside chat with CEO Joe Panetta at the Board of Governors Meeting in San Diego in April. The meeting engaged nearly all of the 70 executives from the life science industry throughout the state who compose the association’s leadership.
- By invitation of San Diego State University Vice Chancellor for Research Dr. Mandanat, Director McCall met with ARPA-H Director Dr. Wegrezyn and U.S. Health & Human Services Secretary Becerra at the Minority-Serving Institutes Summit on Health Care Equity and Access in April, which engaged leaders from across the state to contribute to ARPA-H's next priorities and foster cross-sector collaborations.
- CIAPM helped inspire the Precision Medicine Track at the 2024 National Science Policy Symposium, hosted by UC Riverside and the National Science Policy Network. Director McCall chaired a panel titled “Innovation Strategies for Healthcare,” featuring World Telehealth Initiative Vice President Michael Chan and California Life Sciences
- Director McCall was also featured in a virtual fireside chat with the Executive Director of the National Science Policy Network, Dr. Tepring Piquado.
- As the only state-level government representative, Director McCall was invited to participate in the 2024 White House Summit on STEMM Equity and Excellence: Propelling Progress and Prosperity by 2050 in Washington, DC.
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An Interview with Dr. Sabrina Liu
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CIAPM-funded Project: Using Precision Medicine to Tackle Impacts of Adverse & Unpredictable Experiences on Children’s Neurodevelopment (University of California, Irvine, Lead Investigator: Tallie Z. Baram).
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Sabrina Liu, PhD, is a clinical psychologist and assistant professor of human development at California State University San Marcos.
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What impacts have you seen from this CIAPM-funded project addressing the health impacts of ACEs and advancing health equity?
As we know, ACEs have a tremendous detrimental impact on health and development, and because they are disproportionately distributed among racially and ethnically minoritized populations and low-income populations, they also contribute to persisting health inequities. Therefore, I see our CIAPM-funded project, and all of the CIAPM-funded projects, as having an immense opportunity to advance health equity. I have already seen our work begin to address the health impacts of ACEs through our community-engaged work.
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Depression Research Program
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CIAPM postponed the Expert Selection Committee meeting in March for administrative reasons. The new CIAPM Expert Selection Committee Meeting for the Depression Request for Proposals took place in May during which the Selection Committee recommended awards for three to five research teams ($1.8 to $3 million per team) over a three-year project term.
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Adverse Childhood Experiences (ACEs) Research Program
Staff participated in the second annual site visit for the UCLA ACEs project, titled “Identifying Social, Molecular, & Immunological Processes for Mitigating Toxic Stress & Enhancing Personalized Resilience”. During CIAPM site visits, project teams present research and community updates and engage in fruitful discussions on research directions and impacts.
In addition to CIAPM’s ACEs Research Program, California is dedicated to addressing the health impacts of ACEs. Recently, the Office of the California Surgeon General launched the Live Beyond campaign to increase awareness and understanding of ACEs, toxic stress, and their potential impacts, and provide science-based, healing-centered resources for all Californians.
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CIAPM Network in the News
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UCI ACEs Lead PI, Dr. Tallie Z. Baram, hosted a symposium at the UC Irvine Conte Center on March 26 2024 on “The Power and Potential of Big Data and Consortia for Studying Mental Health and Disease.”
Loma Linda ACEs Lead PI, Dr. Ariane Marie-Mitchell and her team presented a poster entitled “Potential Disparities in Reporting and Referring for Adverse Childhood Experiences” at the Loma Linda’s Diversity and Equity Annual Meeting in February 2024.
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California Precision Medicine Advisory Council
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The California Precision Medicine Advisory Council (CPMAC) met on March 25 to discuss important goals for the Depression Research Program, the Representative Research Collaborative, Federal engagement, and the new Communications portfolio. Minutes for the December 2023 Meeting were approved and are available on our Meetings page.
The next CPMAC meeting will occur on June 11 2024 at 10 a.m. PT, and the agenda and registration link will be posted on our Meetings page.
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Since May is Mental Health Awareness month, we are partnering with the National Institute of Mental Health (NIMH) to highlight several important notices and funding opportunities to contribute to mental health research.
The National Institute of Mental Health (NIMH) issued a Request for Information (RFI) on strategies to advance the relevance and impact of mental health services research. Responses must be submitted by September 30, 2024.
NIMH and the National Institute on Drug Abuse (NIDA) issued a Notice of Special Interest (NOSI) on implementation science research to support the delivery of evidence-based practices in community-based mental or general medical healthcare settings. Rolling applications through May 8, 2025.
NIMH and NIDA issued a Notice of Special Interest (NOSI) on priority research opportunities in crisis response services. Rolling applications through May 8, 2025.
NIMH is issuing a Notice of Special Interest (NOSI) to outline priorities for school-based intervention and services research. Rolling applications between June 5, 2024 and March 17, 2026.
The US Department of Health and Human Services (DHHS) issued a Notice of Funding Announcement (NOFO) to develop precision mental health tools that inform treatment selection in depression. Applications must be submitted by October 18, 2024.
NIMH has a Notice of Funding Announcement (NOFO) for exploratory/ developmental research applications within the learning health care framework to support adoption, implementation, sustainability, and continuous improvement of evidence-based practices in outpatient mental health and substance use treatment systems. Application cycles run through January 8 2026.
DHHS issued a Notice of Funding Announcement (NOFO) to encourage research that addresses the link between social disconnection in late-life and late-life suicidal thoughts and behaviors. Rolling applications through June 5, 2026.
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National Academy for State Health Policy Annual Conference
September 9-11 | Renaissance Nashville Hotel in Nashville, TN
The NASHP conference brings together state leaders to create innovative solutions to rising prescription costs, hospital costs, Medicaid policy, health insurance marketplaces, telehealth, social determinants of health, behavioral health, and more.
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Find more external events on CIAPM's website.
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Find more opportunities at the California Grants Portal
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P.O. Box 3022
Sacramento, CA 95814-3022
(916) 322-2318
info@opr.ca.gov
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