MiTeGen - Innovations For Crystallography and Cryo-EM

High Throughput Tomography (HiTT) on EMBL Beamline P14 on Petra III

High Throughput Tomography (HiTT) on EMBL Beamline P14 on PETRA III

Image Source: Jonas Albers et al. bioRxiv 2023.09.06.556509; doi: https://doi.org/10.1101/2023.09.06.556509

In a preprint at bioRxiv, Jonas Albers et al. "present HiTT – high throughput tomography – a propagation based phase contrast X-ray imaging technique which can visualise 1 mm3 biological samples of various types at high resolution."


They highlight several several benefits of using HiTT including demonstrating "the successful application of HiTT on various soft tissue samples in both liquid (hydrated and also dehydrated) and paraffin embedded preparations." In addition, they "show how the high throughput nature of the work has allowed large numbers of “identical” samples to be imaged to enable statistically relevant sample volumes to be studied."


Our MiTeGen B5 goniometer bases were used as part of this research.

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Do You Have Funds Remaining In Your Budget?

Use Your Funds Before They Expire

This time of year we often hear from customers who have funds remaining in their budget which must be spent before the end of the year. We help them by aligning the products we offer with their needs to ensure those funds are put to good use.


Do you have funds remaining in your budget that must be used? Then contact us today and let us work together to ensure you get the tools, instruments and consumables you need so those funds do not go to waste.

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2024 Beamline For Schools Competition

Beamline For Schools 2024

Registration for the 2024 Beamline for Schools (BL4S) competition is now open. It is a physics competition for high school students organized at CERN and DESY. Teams of high school students can propose an experiment that they want to perform at a beamline.


The teams that submit the three best proposals win a trip to CERN or DESY to perform their experiments at a fully-equipped beamline. Registration ends April 10th 2024.

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Video - Learn The Benefits Of Our Cryo-EM AutoGrid Cassette Puck

AutoGrid Cassette Puck

We understand your need to learn how a tool will benefit your research. That is why we created a video for our cryo-EM AutoGrid cassette puck.


This tool allows users to screen on a Glacios and ship the same AutoGrid cassette puck to a collection facility, or allow facilities to store their cassettes in the puck canes.

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Are You An ACA Member? It's Time To Vote

ACA 2023 Elections

The 2023 ACA (Structural Science Society) election is now live. It's time to review and select your choice of candidates that will help guide the ACA in the future.


Please note that your ACA member number will be required to submit the ballot. Voting remains open until November 29th. 

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What Events Are You Participating In?

We are planning our 2024 event participation - sponsorship schedule and are interested in hearing from you concerning the events you are either considering or will be participating in. This participation can range from attending an event, speaking at it, organizing it, etc.… The survey is short and you can submit it anonymously.

Please Take Our Events Survey

Events, Workshops and Conferences

Events - Workshops- Symposiums - Conferences

If you are looking for more events visit our events page. It lists conferences, workshops, symposiums, user meetings and more.


Topics include structural biology, material science, crystallography, cryo-EM, beamline research and more.

Visit Our Events Page
Industry Resources and News

Here is a small selection of industry resources and news for your browsing.


  • Paper at Acta Cryst F, Making your raw data available to the macromolecular crystallography community - Learn More 
  • Paper at Cell Structure, Review of serial femtosecond crystallography including the COVID-19 pandemic impact and future outlook - Learn More
  • Article at the FEBS Journal, Words of advice on teaching macromolecular crystallography - Learn More 
  • Paper at Acta Cryst F, Using structural genomics depositions in undergraduate teaching of protein crystallography: everybody wins - Learn More 
  • From ACS Central Science, Crystallography Databases Hunt for Fraudulent Structures - Learn More 
  • Paper at Acta Cryst C, Pathological crystal structures (While analyzing the crystallographic results with available software tools can catch many types of errors, others can be detected only by combining knowledge of both crystallography and chemistry - Learn More
  • Paper at IUCrJ, Going around the Kok cycle of the water oxidation reaction with femtosecond X-ray crystallography - Learn More 
  • Paper at UCrJ, Single-crystal quality data from polycrystalline samples: finding the needle in the haystack - Learn More
  • From the CCDC, Open Research Europe authors can now choose the Cambridge Structural Database (CSD) as their repository of choice during the submission process - Learn More 
  • Nature Structural & Molecular Biology (NSMB) is soliciting photos for its 30th anniversary cover - Learn More 
  • From the CCDC Blog, learn how structural data can be used to empower molecular discovery at each step of the drug design pipeline - Learn More
  • Preprint at bioRxiv, PyTME (Python Template Matching Engine): A fast, flexible, and multi-purpose template matching library for cryogenic electron microscopy data - Learn More 
  • Preprint at bioRxiv, CryoTransformer: A Transformer Model for Picking Protein Particles from Cryo-EM Micrographs - Learn More 
  • Preprint at bioRxiv, Integrated Protocol of Protein Structure Modeling for Cryo-EM with Deep Learning and Structure Prediction - Learn More 
  • Learn about EMPIAR, the Electron Microscopy Public Image Archive, is a public resource for raw images underpinning 3D cryo-EM maps and tomograms - Learn More
  • Paper at Acta Cryst D, Increasing the bulk of the 1TEL–target linker and retaining the 10×His tag in a 1TEL–CMG2-vWa construct improves crystal order and diffraction limits - Learn More 
  • Paper at Acta Cryst A, Molecular replacement for small-molecule crystal structure determination from X-ray and electron diffraction data with reduced resolution - Learn More 
  • Canadian Science Publishing has a call for papers on a broad range of scientific topics and applications within chemistry which include experiments conducted at the Canadian Light Source - Learn More 
  • From Lightsources.org, The National Synchrotron Radiation Research Center (NSRRC) commemorates the “30th Anniversary of First Light" - Learn More 
  • Find beamline proposal deadlines from around the world at Lightsources.org - Learn More

Beamline Guide Updated

Updated Beamline Guide

We've updated our Beamline Guides again to include the latest beamline information as well as adding additional beamlines.


The guide is designed to assist you with determining who to contact, how to schedule your beamtime, what sample hardware is needed and more.

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