MiTeGen - Innovations For Crystallography and Cryo-EM

The High-Pressure Freezing Laboratory for Macromolecular Crystallography (HPMX)

High Pressure Freeze Lab at ESRF

Image Source: Carpentier, P., van der Linden, P. & Mueller-Dieckmann, C. (2024). Acta Cryst. D80, 80-92.

In a paper at Acta Crystallographica Section D, Philippe Carpentier et al. discuss the research at the High-Pressure Freezing Laboratory for Macromolecular Crystallography at ESRF. The lab provides "additional and complementary functionality to the diffraction, scattering, and imaging beamlines of the SB Group. The platform is dedicated to the preparation of gas derivatives of macromolecular crystals and to the investigation of interactions between macromolecules and gases in crystallo." Methods, instrumentation, applications, and examples are discussed.


Our MiTeGen High Pressure Crystallography Supports, Pins, and Bases are designed for use at the lab.

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High-Pressure Crystallography Supports Pins and Bases

High Pressure Crystallography Supports Pins and Bases

These supports, pins, and bases are for high-pressure freezing macromolecular crystallography (HPMX) research. Easy connector-style insertion and removal allow samples to be prepared in high-pressure freezing configurations and then assembled for automated sample handling and goniometer placement at the beamline.


It comes with small diameter polyimide tubing inserted into the pin but can be ordered with MiTeGen MicroMounts - MicroLoops attached instead.

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ACA Annual Meeting Abstract Submission Deadline

ACA Annual Meeting Abstract Submission Deadline

The deadline for submitting an abstract for the ACA Annual Meeting is Friday, March 29th, at 11:59 PM, Eastern. This is your chance to showcase your research to leading experts in the field of structural science. 


Sessions will include presentations by invited speakers and talks based on submitted abstracts. The Oxford Abstract system will be used to collect abstracts for ACA2024.

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New Product - 8 Pocket Grid Box

8 Pocket Grid Box

The 8-pocket grid box is unique in that it allows the storage of 8 unclipped grids in one grid box. The traditional diamond-shaped pocket provides security for an unclipped grid while also allowing for easy access with tweezers. The grid box comes in 6 colors and has a unique 5-digit serial number on each box.


Available in several pin lid options, including plastic, metal, or low profile pin lid type.

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The Annual ACA Summer Course Open For Registration

ACA Summer Course

The ACA Summer Course will be held from June 23rd to the 30th at Purdue University. It is directed towards Single-Crystal Chemical Crystallography and Powder Diffraction techniques, as applicable to small molecule studies. It is designed to instruct attendees in the theory and practice of these two aspects of crystallography.


A few open spaces remain for those interested in attending the course. (See button below)

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Upcoming Events

Frontiers in Chemistry and Biology Interface Symposium

The Frontiers at the Chemistry-Biology Interface Symposium (FCBIS) is May 4th in Baltimore, MD. The symposium is a day-long event designed to highlight the latest in cutting-edge research in the Mid-Atlantic region and provide an intimate environment to foster scientific discussion at all levels. We are a proud sponsor of the symposium.

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APS/CNM Users Meetings

The APS/CNM Users meeting is May 6th to the 10th at Argonne National Laboratory in Lemont, IL.

The meeting will feature workshops, talks, a poster session, meeting banquet and vendor exhibit. We are sponsoring and exhibiting at the meeting. Stop by our booth to see our latest innovations for crystallography and cryo-EM.

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Events, Workshops and Conferences

Events - Workshops- Symposiums - Conferences

If you are looking for more events, please visit our events page. It lists conferences, workshops, symposiums, user meetings, and more.


Topics include structural biology, material science, crystallography, cryo-EM, beamline research, and more.

Visit Our Events Page
Industry Resources and News

Here is a small selection of industry resources and news for your browsing.


  • Paper at Acta Cryst A, Machine learning in crystallography and structural science - Learn More
  • Paper at Nature Structural & Molecular Biology, Celebrating Nature Structural & Molecular Biology’s 30th anniversary - Learn More
  • SBGrid Consortium YouTube Channel, Features videos from events hosted by SBGrid on EM, crystallography, structure analysis, computational chemistry, and more - Learn More
  • Paper at IUCrJ, Poetry in motion: catching molecules in action - Learn More
  • Blog post at CCDC, 1.3 Million and Beyond – The 2024 March Data Update - Learn More 
  • The Biophysical Society is now accepting nominations for its 2025 award cycle. Awards available in sixteen different categories - Learn More
  • Book review at Acta Cryst D, Dynamics, and Kinetics in Structural Biology: Unravelling Function Through Time-Resolved Structural Analysis - Learn More 
  • Paper at Acta Cryst D, Single-crystal X-ray diffraction, and small-angle X-ray scattering were used to study the nucleprotein of Toscana virus complexed with a single-chain camelid antibody - Learn More
  • Paper at Acta Cryst D, A service-based approach to cryoEM facility processing pipelines at eBIC - Learn More
  • EMBL Grenoble is launching a Grenoble Club for CryoEM Enthusiasts. The club is created to connect the local research community with an interest in all aspects of cryo-electron microscopy, from sample preparation to data analysis and beyond - Learn More
  • Paper at Nature Communications, High-resolution cryo-EM of the human CDK-activating kinase for structure-based drug design - Learn More
  • Paper at Nature Communications, Functionalized graphene-oxide grids enable high-resolution cryo-EM structures of the SNF2h-nucleosome complex without crosslinking - Learn More
  • Post at Lightsources.org, Exploring Matter at or under Extreme Conditions at Diamond - Learn More
  • Technical Report at Synchrotron Radiation News, Materials Discovery at BESSY - Learn More
  • A new program from the APS, called eBERlight, aims to connect the world-leading X-ray facility with more scientists studying Earth’s climate, environment and bioeconomy crops - Learn More
  • Advanced Light Source is accepting applications from doctoral students and postdoctoral associates to spend a year in residence conducting research at the ALS starting in September 2024 - Learn More
  • Find beamline proposal deadlines from around the world at Lightsources.org - Learn More

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