April 24, 2023

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WEEKLY HIGHLIGHT

Cisplatin

Drug Shortage


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Summer Meeting Registration is Open!

The NRG Oncology 2023 Summer Meeting is now open for registration! The Meeting will be held in Philadelphia from Thursday, July 20, 2023 - Saturday, July 22, 2023. Sessions will be held in-person and available via streaming unless noted. Additionally, there will be virtual-only sessions on Monday and Tuesday, July 17-18, 2023. Click here to Register Today!

 


ACTIVATION

GYNECOLOGIC

NRG-GY024: Activated for Canadian sites, effective April 24, 2023. Activation memo and Canadian PSR documents are now available on NRG Oncology.


CLOSURES

BRAIN

NRG-BN010: Temporary Closure Notice dated April 18, 2023 (posted on CTSU). The trial is temporarily closed to accrual for a protocol-specified analysis of safety and tolerability.

 

BREAST

NRG-BR007/DEBRAClosure to Accrual to the HRQOL Sub-study. Please see the memorandum (posted on CTSU) for details.

 

GASTROINTESTINAL

NRG-GI007: Temporary Closure Notice dated April 21, 2023 (posted on CTSU). The trial is temporarily closed to accrual for a protocol-specified analysis.


OTHER PROTOCOL NOTICES

1. ALL DISEASE SITES

NRG-GY022: Reminder: Actively Recruiting MALE Patients only Read More

 

2. CANCER PREVENTION & CONTROL

NRG-CC005/FORTE: Join the next FORTE site call on May 17 at 4pm EDT, an informal discussion on study progress and conduct with the NRG FORTE team, featuring Kaiser Permanente representatives to share about their screening and enrolling processRegister today at this link!


NRG-CC009: An updated patient brochure and CIRB approval of the document are available on CTSU. A patient study web page is available on NRG Oncology.


3. GASTROINTESTINAL

NRG-GI004/SWOG S1610 (COMMIT): The Amendment 9 Overview webinars are being held on May 16 at 10am EDT and 4pm EDT. Please see the memorandum (posted on CTSU) for details and how to register for one of the sessions.


NRG-GI005 (COBRA) / NRG-GI008 (CIRCULATE-US): The webinar “Surgical implications of ctDNA: Is this the future for colon cancer?” is being held on April 26 and May 4. Please visit the NRG Oncology website or see the memorandum (posted on CTSU) for details and how to register for one of the sessions.

 

4. GENITOURINARY

NRG-GU008: The Spanish-translated consent forms and CIRB approval of the forms are available on CTSU.

 

5. GYNECOLOGIC 

GOG-0210: Reminder: Biospecimens, biomarker data, clinical data, and epidemiologic data are available for request. Please visit the NRG Oncology website for more information on this important study with the overall goal of improving the outcome and/or quality of life for patients with endometrial cancer.

 

NRG-GY012 and NRG-GY023 – Reminder: BLOOD PRESSURE CUFF SUPPLY IS VERY LIMITED - Please be advised that VWR has a very limited supply of blood pressure cuffs at present. Please check your supplies on site for any overlooked cuffs prior to ordering. Thank you for your cooperation. 

 

Printing Biospecimen Transmittal PDFs on GYN Trials

Please note an effort is underway to clarify how to obtain a Biospecimen Transmittal PDF for submission to the NRG Oncology Biospecimen Bank. Read More


6. HEAD & NECK

NRG-HN008: Reminder! please update treatment and AE data weekly. This is a Phase I trial and timely data submission is very important. 

 

7. VTOC TRAINING

The VTOC Webinar Training Series schedule and registration is available for NRG Oncology Research Associates working on RTOG 0924, RTOG 0920, NRG-HN001, NRG-HN002, NRG-CC003, NRG-CC005, and NRG/SWOG S1914. Space is limited so register now and reserve your seat. The next webinar training is scheduled for Wednesday, May 3, 2023. 

 

DRUG SAFETY UPDATES

Drug Safety updates have been issued for the following studies:

DRUG NAME

PROTOCOL

WEBSITE FOR SAFETY REPORTS

Atezolizumab



NRG-BN010

NRG-BR004

NRG-GI004/SWOG-S1610

NRG-GY009

NRG-LU002

NRG-LU005

NRG-LU007

RTOG 1216


CTSU

CTSU

CTSU

CTSU

CTSU

CTSU

CTSU

CTSU


Capivasertib

NRG-GY012

CTSU

Durvalumab

NRG-GY012

NRG-GY023

NRG-HN004

NRG-LU004

RTOG 1308


CTSU

CTSU

CTSU

NRG

CTSU


Nivolumab

NRG-GY025

NRG



Cisplatin Drug Shortage

There is currently a shortage of cisplatin nationwide. The following NRG studies involve the use of commercial Cisplatin.

  • NRG-GY019
  • NRG-GY024
  • NRG-HN001
  • NRG-HN005
  • NRG-HN009
  • NRG-LU006
  • NRG-RTOG 1216
  • NRG-RTOG 1308

Please review the memo for recommended strategies for enrolling participants in NRG trials involving Cisplatin.

 

NRG Cancer Care Delivery Webinar – Register today!

Register for the upcoming webinar hosted by the NRG Cancer Care Delivery Committee: Advancing equity in artificial intelligence for cancer care delivery

Cancer care delivery increasingly employs artificial intelligence tools to improve diagnosis, treatment selection, and health system efficiency. As tool integration progresses in clinical care settings, practitioners should be intentional about equitable implementation and knowledgeable about algorithmic fairness, which may exacerbate current health disparities. This webinar will address current artificial intelligence initiatives poised to promote fairness and health equity in optimizing cancer care delivery. This session will be held on April 26, 2023, 2 – 3:30pmEST and co-lead by Dr. Julian Hong of the University of California, San Francisco and Dr. Anant Madabhushi of Emory University. Please view the flyer here.



Click here to register for the webinar

NRG Oncology is pleased to report the scientific article that appeared during the previous week. This publications report includes the link to the article.

 

JOURNAL ARTICLES

This article is a republication (JCO.1998.16.8.2672) as part of the JCO 40th Anniversary Flashback Series: Fisher B, Bryant J, Wolmark N, Mamounas E, Brown A, Fisher ER, Wickerham DL, Begovic M, DeCillis A, Robidoux A, Margolese RG, Cruz AB Jr, Hoehn JL, Lees AW, Dimitrov NV, Bear HD. Effect of preoperative chemotherapy on the outcome of women with operable breast cancer. J Clin Oncol. 2023 Apr 1;41(10):1795-1808. doi: 10.1200/JCO.22.02571. PMID: 36989610. Read more.


Please note the following upcoming meeting and abstract submission deadlines


UPCOMING MEETINGS

American Association for Thoracic Surgery (AATS); May 6-9, 2023; Los Angeles, CA


American College of Radiology (ACR); May 6-10, 2023; Washington, DC


American Society of Clinical Oncology (ASCO); Jun 2-6, 2023; Chicago, IL


ESMO Breast Cancer Annual Congress; May 11-13, 2023; Berlin, Germany


European Society for Radiotherapy and Oncology (ESTRO); May 12-16, 2023; Vienna, Austria


Society for Clinical Trials (SCT); May 21-24, 2023; Baltimore, MD


Western Association of Gynecologic Oncologists (WAGO); Jun 14-17, 2023; Monterey, CA

 

UPCOMING ABSTRACT SUBMISSION DEADLINES

American Society for Radiation Oncology (ASTRO); Oct 1-4, 2023; Chicago, IL; LBA Jul 12, 2023


ESMO World Congress on Gastrointestinal Cancer; Jun 28-Jul 1, 2023; Barcelona, Spain; LBA Jun 15, 2023


European Society of Gynaecological Oncology (ESGO); Sep 28-Oct 1, 2023; Istanbul, Turkey; due to publications committee Apr 24, 2023; meeting submission deadline May 8, 2023; LBA Aug 7, 2023


European Society for Medical Oncology (ESMO) Congress; Oct 20-24, 2023; Madrid, Spain; due to publications committee Apr 26, 2023; meeting submission deadline May 10, 2023, 9pm CntEurSummerTime (CEST); LBA Sep 14, 2023, 9pm CEST


International Gynecologic Cancer Society (IGCS); Nov 5-7, 2023; Seoul, South Korea; due to publications committee Apr 24, 2023; meeting submission deadline May 8, 2023, Abstract & Film; TiP LBA, Aug 21, 2023


International Society for Quality-of-Life Research (ISOQOL); Oct 18-21, 2023; Calgary, AB Canada; LBA Jul 7, 2023


Radiological Society of North America (RSNA); Nov 27-Dec 1, 2023; Chicago, IL; due to publications committee Apr 19, 2023; meeting submission deadline May 3, 2023, 12 Noon CT

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