July 21, 2016 
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NAVBO members receive discounts on registration to IVBM 2016
Vasculata 2016
Uppsala University
University of Pennsylvania
August 15-17
Look inside the IVBM Virtual Conference Bag

Lymphatic Forum
in Chicago, IL
June 8-10, 2017

Vascular Biology 2017
Monterey, CA
October 15-19 
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Meet our New Council Members
Cecilia M. Giachelli, Ph.D., Professor
Hunter and Dorothy Simpson
     Endowed Chair of Bioengineering
University of Washington

Dr. Giachelli received her undergraduate training in Biochemistry from the University of California at Davis and the doctoral degree in Pharmacology from the University of Washington.  In 1999, she joined the UW Bioengineering department as Assistant Professor and Deputy Director of the NSF-sponsored Engineering Research Center, UW Engineered Biomaterials.  She is currently the Hunter and Simpson Endowed Chair of Bioengineering.

Dr. Giachelli is internationally recognized for her work investigating the molecular mechanisms of vascular calcification and extracellular matrix control of cell function. Her studies have led to the discovery of key inducers and inhibitors that contribute to vascular calcification in the setting of chronic kidney disease, valve disease, atherosclerosis and medical devices.  These discoveries are currently being translated to therapeutic strategies to block inappropriate calcification in disease and biomaterials development. Other key areas of research include control of inflammation and foreign body reaction, regenerative medicine, cell and tissue engineering.

Dr. Giachelli is an elected fellow of the American Institute for Medical and Biological Engineering and the Washington State Academy of Sciences, and recipient of the American Heart Association Established Investigator Award, the Advances in Mineral Metabolism Investigator Award, and the American Society of Nephrology's Jack W. Coburn Lectureship.

IVBM Abstract Submission Deadline is July 26
19th International Vascular Biology Meeting
Boston - October 30-November 3
Abstract Deadline - July 26 (only 5 days left to submit)
Early bird registration deadline - August 15
Hotel reservations - October 8
Stream Vasculata to Your Institution
Vasculata 2016
Uppsala/Philadelphia - August 15-17

If you can't come to Vasculata - have Vasculata come to you!
Bring the live streaming web cast of Vasculata to your institution.Have access to talks from 23 international speakers in sessions covering: 
  • Vascular Development: Cell Biology and Morphogenesis
  • Vascular Specialization and Blood Vessel Diseases
  • The Lymphatic and "Glymphatic" Systems
  • Blood-Brain Barrier and Blood Flow Regulation in the Brain
What you should plan - make the web cast available to a broad audience at your institution by showing it in a single conference room or auditorium. Enlist facilitators to moderate the sessions.  Be sure to have high quality audio-visual equipment to ensure smooth operation.

There is a registration fee of $1,000 per institution for an unlimited number of attendees within that institution.

More information is available on the web site at http://www.navbo.org/events/vasculata-2016/webcast or contact the NAVBO office if interested and if you have any questions - info@navbo.org.


Award Opportunity
Warren Alpert Foundation Prize 
The Warren Alpert Foundation invites nominations for the 2017 Warren Alpert Foundation Prize. Nominations should be made for scientific achievements that have led to the prevention, cure, or treatment of human disorders or for research for seminal scientific research findings that holds great promise to change our ability to treat disease.
The unrestricted cash award accompanying the prize is U.S. $500,000, a citation and plaque. The recipient(s) of the 2017 Warren Alpert Foundation Prize will also participate in a special symposium in their honor at Harvard Medical School. Nominations are accepted from academic institutions, centers of research, government, or other biomedical institutions from around the world. Self-nominations are not accepted. To nominate, please visit the Warren Alpert Foundation Prize nomination page at  http://warrenalpert.org/nominations . The deadline for receipt of nominations is October 31, 2016.
Lab of the Month
The Lab of Dr. A. Wayne Orr
This month we are highlighting the lab of Dr. A. Wayne Orr of the Louisiana State University Health Sciences Center - Shreveport. Find out more about Dr. Wayne's lab at   http://www.navbo.org/membership/members-labs/529-lab072016.
View all featured laboratories at navbo.org/membership/members-labs.
Member News
Meet one of our newest members:
Dr. Kowalski obtained his PhD from the University of Groningen in the Netherlands, where we worked in the group of Prof. Grietje Molema on the development of lipid-based system for specific delivery of short interfering RNAs to inflamed endothelium. He is currently appointed as a postdoctoral associate in the laboratory of Prof. Daniel G. Anderson at the Koch Institute for Integrative Cancer Research at MIT, exploring therapeutic potential of messenger RNA and developing novel nanotechnologies to facilitate the in vivo delivery of mRNA. Dr. Kowalski has a great interest in biomedical research focusing on applications of drug delivery, nanotechnology and gene therapy to vascular biology and cancer with an aim to develop novel therapies for life-threatening or debilitating diseases. 

Welcome our new members:
Sabu Abraham, Institute of CardioVascular Sciences
Sabine Bailly, INSERM
Sara Benedetti, University College London
Karim Brandt, University of Geneva
Sergio Esteban, CNIC
Xiao Fu, Indiana University Bloomington
Vijay Ganta, University of Virginia
Tamara Girbl, Queen Mary University of London
Rebecca Izen, National Heart, Lung, and Blood Institute
Xintong Jiang, Karolinska Institute
Igor Kovacevic, VU University Medical Center
Kevin Kruse, University of Illinois, Chicago
Chin Nien Lee, Boston Children's Hospital
Madeline Midgett, Oregon Health & Science University
Sumathy Mohan, University of Texas HSC/San Antonio
Cindy Park-Windhol, Harvard Medical School
Laura Pisarsky, Fred Hutchinson Cancer Research Center
Manon Pronk, VU Medical Center
Bianca Rich, University of Utah
Song-Kun Shyue, Academia Sinica
Kaela Varberg, Indiana University
Nuria Villalba, University of Vermont
Nejla Yosef, Baylor College of Medicine
An Zwijsen, VIB VZW

If you have news to share with your colleagues, send it to membership@navbo.org.
Spotlight on Trainees
Congratulations to our GRC Travel Award Recipients
Austin McDonald of the UCLA-Caltech Medical Scientist Training Program and Emma Watson of the Walter and Eliza Hall Institute of Medical Research in Australia were chosen as the recipients of NAVBO's Trainee Travel Awards for the Gordon Research Conference on Endothelial Cell Phenotypes in Health & Disease.  The conference finishes up tomorrow, July 22.

Trainee Members:  Are you interested in joining the NAVBO Membership Committee?
The Membership Committee is tasked with developing and publicizing the benefits of belonging to NAVBO, and ensuring that NAVBO responds to the needs of its membership. That includes trainee members, so we need your help!

The NAVBO Membership Committee has issued a Call for Applications for trainees interested in joining the Committee. Applicants should expect to serve a minimum of three years. Applications must include:  your CV, a letter from your supervisor attesting to your leadership quality, a brief statement from you concerning your commitment to the society and the vascular biology community, and what you would like to bring to this committee.
Please send this information to membership@navbo.org by August 1.
Product Showcase
Excellence from the European Heart Journal 
Discover leading cardiology research with the European Heart Journal, the fl agship title of the European Society of Cardiology. Ranked third in the field, publishing high quality clinical and scientific papers relating to all aspects of cardiovascular medicine, the EHJ is the prime place to read and submit the best research.
 Recent Publications by NAVBO Members

MicroRNA-181b inhibits thrombin-mediated endothelial activation and arterial thrombosis by targeting caspase recruitment domain family member 10
FASEB Journal
Thrombogenic and inflammatory mediators, such as thrombin, induce NF-?B-mediated endothelial cell (EC) activation and dysfunction, which contribute to pathogenesis of arterial thrombosis. The role of anti-inflammatory microRNA-181b (miR-181b) on thrombosis remains unknown.  Read more

Scavenger receptor class A member 5 (SCARA5) and suprabasin (SBSN) are hub genes of coexpression network modules associated with peripheral vein graft patency
Journal of Vascular Surgery
OBJECTIVE: Approximately 30% of autogenous vein grafts develop luminal narrowing and fail because of intimal hyperplasia or negative remodeling. The authors previously found that vein graft cells from patients who later develop stenosis proliferate more in vitro in response to growth factors than cells from patients who maintain patent grafts.  Read more

Pericardial patch venoplasty heals via attraction of venous progenitor cells
Physiological Reports
Pericardial patches are commonly used during cardiovascular surgery to close blood vessels. In arteries, patches accumulate arterial progenitor cells; the authors hypothesized that venous patches would accumulate venous progenitor cells, in the absence of arterial pressure.  Read more

Membrane-mediated regulation of vascular identity
Birth Defects Research. Part C, Embryo Today: Reviews
Vascular diseases span diverse pathology, but frequently arise from aberrant signaling attributed to specific membrane-associated molecules, particularly the Eph-ephrin family. Originally recognized as markers of embryonic vessel identity, Eph receptors and their membrane-associated ligands, ephrins, are now known to have a range of vital functions in vascular physiology.  Read more

Embryological Origin of Human Smooth Muscle Cells Influences Their Ability to Support Endothelial Network Formation
Stem Cells Translational Medicine
Vascular smooth muscle cells (SMCs) from distinct anatomic locations derive from different embryonic origins. Here the authors investigated the respective potential of different embryonic origin-specific SMCs derived from human embryonic stem cells (hESCs) to support endothelial network formation in vitro.  Read more

Job Postings
Job Title
University of California, San Francisco
San Francisco, CA
Postdoctoral Fellowship
University of Pittsburgh
Pittsburgh, PA
Yale University School of Medicine
New Haven, CT
Calendar of Events
Aug. 15-18 Vasculata 2016
Sept. 7-10 ISACB - 15th Biennial Meeting
Sept. 26-28 Perspectives in Vascular Biology
Oct. 30 - Nov. 3 19th International Vascular Biology Meeting
Nov. 13-16 American Society for Matrix Biology Biennial Meeting
June 8 - 10 Lymphatic Forum 2017
Industry News
Repercussions of Brexit for life sciences research
The Guardian
The Guardian reports heightened levels of   concern in the UK that withdrawal from the European Union will have a chilling effect on basic life sciences research and translational medicine. Public scientific research in Britain employs some 100,000 researchers and produces publications second in citation only to the US. As a leading enterprise, research is one of the many areas likely to suffer if Britain leaves the EU. Three-quarters of the increase in scientific funding to universities has come from the EU over the last few years. 

Crispr/Cas9 technology adapts porcine vasculature for human compatibility
Investigators in academia and in private ventures have taken advantage of the specificity and efficiency of Crispr/Cas9-directed gene modification in efforts to produce a steady and safe source of tissues, including hearts blood vessels for human transplantation. In 2014, United Therapeutics formed a partnership with the biotech firm Synthetic Genomics (SGI). SGI is engineering tissues displaying receptors that sequester human immune signaling factors that would otherwise attack the organ.
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From the app stores, search NAVBO Events or scan the appropriate QR code:

Please note - more sessions and more information will continue to be added.
Eye Opener Sessions have now been added.

North American Vascular Biology Organization | bernadette@navbo.org | http://www.navbo.org
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Germantown, MD 20874-2211