For the latest updates, trends, and opportunities for all things
multipurpose prevention technologies (MPTs)
Dear MPT Insiders,

As the year comes to an end, we’re happy to share one more newsletter bringing the most recent research, news, events, resources and opportunities in the MPT field to you. Find out about our upcoming "Let's Talk MPTs" Webinar and more below!

Thank you for your continued partnership with the IMPT. We look forward to reconnecting with you in 2023!

The Secretariat Staff
IMPT Highlights
Save the Date! Sexually Transmitted Infections: Public Health Status and Opportunities for Multipurpose Prevention Technologies

This upcoming webinar in our “Let’s Talk MPTs” series will feature discussion from a range of experts in the HIV and sexually transmitted infections (STIs) prevention fields to discuss topics including current trends in STIs and opportunities and challenges for MPTs that target STIs. The webinar will take place Thursday 12 January 2023. Featured speakers are James Cummins (NIAID), Ina Park (UCSF Department of Family and Community Medicine) and Katherine Yang (UCSF School of Pharmacy). Save the date to join us!
Call for Papers!
We are very pleased that Frontiers in Reproductive Health will be publishing two complementary special issues on MPTs over the next year. The first special issue, “Multipurpose Prevention Technologies for HIV, STIs and Pregnancy” will focus on the current status of MPTs for women, with articles covering formulation science, clinical trials, socio-behavioral research, and implementation research in a “bench to bedside” approach. The deadline for Manuscript Extension submission is 16 January 2023 (read more here).

The second special issue, “Multipurpose Prevention Technologies: Call for Innovative Strategies to Address Critical Priorities and Gaps” will focus on innovative approaches to address priorities and gaps to advance the MPT field, and seeks papers from MPT developers and other stakeholders that are relevant to the MPT field. The deadline for Abstract submission to the second issue is 20 April 2023 and Manuscript submission is 20 June 2023 (read more here).
ICFP 2022 Presentation
The IMPT presented in collaboration with CIFF and UNITAID on MPTs as a part of a panel, "Investing in contraceptive R&D to reduce the unmet need for family planning," at the 6th annual International Family Planning Conference that took place in Thailand this November! If you missed it, you can view our presentation here.

Bi-Annual MPT SACC Meeting
In December, our MPT SACC (Supporting Agency Collaboration Committee) convened to to refine key action areas and strategies to address priorities and gaps for MPT field. The SACC is comprised of representatives from a growing number of government agencies, private foundations, and other MPT supporters worldwide. Established in 2013, the mission of the SACC is to facilitate collaboration and consensus among supporting agencies, maximizing the efficiency and effectiveness of MPT funding.
MPT Research Articles

Preferences for Multipurpose Technology and Non-oral Methods of Antiretroviral Therapy Among Women Living With HIV in Western Kenya: A Survey Study. Bernard, et al. (2022). Frontiers in Global Women's Health. https://doi.org/10.3389/fgwh.2022.869623


Correlates of Dapivirine Vaginal Ring Acceptance among Women Participating in an Open Label Extension Trial. Mirembe, et al. (2022). AIDS and Behavior. https://doi.org/10.1007/s10461-022-03841-z



Evaluating Islatravir Administered Via Microneedle Array Patch for Long-Acting HIV Pre-exposure Prophylaxis Using Physiologically Based Pharmacokinetic Modelling. Kinvig, et al. (2022). European Journal of Drug Metabolism and Pharmacokinetics. https://doi.org/10.1007/s13318-022-00793-6     


Reservoir-Style Polymeric Drug Delivery Systems: Empirical and Predictive Models for Implant Design. Li, et al. (2022). Pharmaceuticals. https://doi.org/10.3390/ph15101226


Translating diagnostics and drug delivery technologies to low-resource settings. Euliano, et al. (2022). Science Translational Medicine. https://doi.org/10.1126/scitranslmed.abm1732

Long-acting HIV pre-exposure prophylaxis (PrEP) approaches: recent advances, emerging technologies, and development challenges. Agrahari, et al. (2022). Expert Opinion on Drug Delivery. https://doi.org/10.1080/17425247.2022.2135699

A Holistic Review of the Preclinical Landscape for Long-Acting Anti-infective Drugs Using HIV as a Paradigm. Neary, et al. (2022). Clinical Infectious Diseases. https://doi.org/10.1093/cid/ciac685

The LEAP Process: Streamlining the Development of Long-Acting Products and Formulations for Infectious Diseases. Flexner, et al. (2022). Clinical Infectious Diseases. https://doi.org/10.1093/cid/ciac750


Interrogating the promise of long-acting HIV pre-exposure prophylaxis. Pike & Bekker. (2022). Trends in Molecular Medicine. https://doi.org/10.1016/j.molmed.2022.11.003

Progestins of today and tomorrow. Liu, et al. (2022). Current Opinion in Obstetrics and Gynecology. https://doi.org/10.1097/GCO.0000000000000819
MPTs in the Media
Upcoming Conferences and Key Dates
January 12-13, 2023 | Reproductive Ethics Conference (Galveston, USA)
The 2023 Reproductive Ethics Conference will convene professionals across various fields in Galveston, Texas to explore the range of topics addressed in reproductive ethics. From 12 to 13 January, discussions will focus on controversies and challenges of reproductive ethics posed by new technologies, political and ideological divisions, theology, and changing cultural norms. Register for the conference here
 
February 15-16, 2023 | Reproductive Health Innovation Summit (Boston, USA)
The 3rd annual Reproductive Health Innovation Summit will take place in Boston, Massachusetts this upcoming year. This summit offers participants the opportunity for reproductive health entrepreneurs and potential investors to network. IMPT director and co-founder, Bethany Young Holt, along with other IMPT partners will attend as speakers and participants. If you plan to attend, please let us know. We're looking forward to engaging with you in person!
February 19-22, 2023 | Conference on Retroviruses and Opportunistic Infections (Seattle, USA)
The 2023 Conference on Retroviruses and Opportunistic Infections (CROI) will convene in Seattle, Washington to present, discuss, and critique investigations into the epidemiology and biology of human retroviruses and associated diseases. Attendance at the conference is open to researchers and clinical educators actively involved in the study and management of HIV, other retroviruses, and related medical conditions. Registration is open now!
April 14-15, 2023 | Sperm | Health | Politics Conference (New Haven, USA)
This conference will convene a focused group of scholars, scientists, and clinicians who are rethinking and reframing male sexual and reproductive health in the United States. Each attendee will be asked to draft a short “thinkpiece” (500 to 1000 words), identifying what they perceive as the most pressing issues related to sperm/health/politics. Those interested in attending can find out more about the conference here and apply by 20 January 2023.
April 28 - May 1, 2023 | Association of Clinical Research Professionals (Dallas, USA)
The Association of Clinical Research Professionals (ACRP) supports clinical research professionals through membership, training and development, and certification. Attend ACRP 2023 to learn strategies, best practices, and creative solutions for improving clinical trial quality and advancing your career. Learn more and register for this upcoming conference here.

October 22-26, 2023 | 5th HIV Research for Prevention Conference (Lima, Peru + virtual)
The only global conference on HIV prevention research, HIVR4P, will bring together 1500 participants to foster interdisciplinary knowledge exchange on HIV vaccines, microbicides, PrEP, treatment as prevention and biomedical interventions, as well as their social and behavioral implications. This year's focus will be on overcoming HIV as a threat to public health and individual wellbeing, including in Latin America, where HIV cases are on the rise.
Contact us if you or your colleagues are attending any upcoming meetings where MPTs will be featured. We’re happy to provide materials to help enhance your presentations. We’d also love to include any materials that you share with us from recent MPT relevant events in our MPT Resource Center.
Funding Opportunities

A few current opportunities can be found below. See other available opportunities here.

Request for Applications 2022-054: MATRIX Technology Accelerator Domain 1
Applications are now open for MATRIX’s, a USAID funded project, Technology Accelerator Domain 1. Applicants from US, Kenyan, South African, and Zimbabwean institutions are invited to apply for this opportunity for funding to advance research applications for development of new HIV prevention approaches. They are seeking innovative research applications for the development of new HIV prevention drugs and strategies, multipurpose prevention technologies (MPTs), and technologies that enable HIV prevention strategy development and have the potential to strengthen capacity in targeted countries. For more information and to apply, visit the MATRIX website
  • Open Date: 01 December 2022
  • Letters of Intent Due: 01 February 2023
  • Application Due: 03 March 2023

Development of Novel Nonsteroidal Contraceptive Methods (R61/R33 - Clinical Trial Not Allowed)
This funding opportunity from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) will support and facilitate multidisciplinary research approaches for the development of novel nonsteroidal contraceptive products for men and women that act prior to fertilization – including potential MPT products. While aiming to position validated methods for clinical development, the award also encourages innovative ideas and supports early stage, high-risk projects lacking validation. Additional details can be found here or at www.GRANTS.gov by searching within “Search Grants” for Funding Opportunity Number: RFA-HD-24-002, then clicking on the opportunity number.
 
  • Funding Opportunity #: RFA-HD-24-002
  • Open Date: 28 February 2023
  • Letters of Intent Due: 30 days prior to application receipt date
  • Next Application Due: 29 March 2023
Fellowship & Career Opportunities

Are you interested in career pathways in MPT research? See resources here!

IAS HIV Vaccine Science Academy Applications 
The IAS Global HIV Vaccine Enterprise will award fellowships to 15 early- to mid-career scientists to receive training in workshops related to HIV vaccine research with international experts. This program is a collaboration with the South African Department of Science and Innovation as well as Health Sciences Faculty at the University of Witwatersrand. The deadline for applications is Sunday 15 January 2023. For more information, see here
We need your support to help make MPTs a reality for those who need them most. Consider making a donation to the IMPT today! 
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