HIRN FUNDING ANNOUNCEMENT: CATALYST AWARD |
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The Human Islet Research Network (HIRN) announces a new funding initiative to support investigators in developing bold, innovative, and challenging projects that will catalyze the diabetes research field and provide important advances in topics of interest to the network. Applicants must propose aims focused on an original scientific idea or question that is distinct from current HIRN funded research. The scientific focus of application to the HIRN Catalyst program must fall within the purview of one (or more) of the current HIRN consortia. Foreign applications not eligible.
Key Dates
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Posted Date:
Letter of Intent Due Date:
Application Due Date:
Scientific Review:
Start Date:
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December 1, 2021
March 1, 2022
May 2, 2022
May – July, 2022
August 1, 2022
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Data Enhancement Achievement: HIRN & IIDP |
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The Integrated Islet Distribution Program (IIDP) and Human Pancreas Analysis Consortium (HPAC) of the Human Islet Research Network (HIRN) have collaborated to integrate the Human Pancreas Analysis Program (HPAP) Pancreas Database (PANC-DB) and IIDP Human Islet Phenotyping Program (HIPP) portal. This integration allows users to view the HPAP hormone secretion traces using the interactive graphing and display capabilities of IIDP. Users can access this new functionality by visiting the HPAP PANC-DB website and selecting the IIDP Islet Function tab from the donor record view. Initially 58 PANC-DB records have been integrated, with plans to incorporate additional records in the future.
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Dr. Rafael Arrojo e Drigo, Assistant Professor, Department of Molecular Physiology and Biophysics, Vanderbilt University will be presenting this webinar on Friday, April 8, 2022, 11:00 am - 12:00 pm Pacific. Learn more HERE.
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dkNET SUMMER OF DATA STUDENT PROGRAM |
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2022 dkNET Summer of Data Student Program
Application Due Date: April 18, 2022
Duration: 6 weeks starting June 13 to July 22, 2022.
The Summer of Data program provides students the opportunity to learn data management, FAIR data and rigor and reproducibility skills while performing their research. It is a 6 week virtual summer program where students engage in weekly sessions with dkNET staff and associates to learn about how to use dkNET and other tools to support their research, while engaging in research projects within their labs. A $1,000 stipend is provided.
Program Description:
The intent of this program is to enable students, over a 6-week period, to use the dkNET portal to support their own research or that of their PI’s. The intent is that they will learn best practices to enhance rigor and reproducibility and learn the basics of good data management by following the FAIR (Findable, Accessible, Interoperable, Reusable) data principles.
Preferences will be given to those research projects that would most benefit from the types of services offered by dkNET, e.g., projects that involve antibodies, genetically modified organisms, and ‘omics’ data in the areas of focus for NIDDK including diabetes, obesity, nutrition, digestive, kidney, liver, urologic, endocrine, metabolic, bone, and blood diseases.
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Modern Phenotypic Drug Discovery: From Chemical Biology to Therapeutics
Phenotypic drug discovery (PDD) as an approach to drug discovery and chemical biology has been building momentum and excitement in both academia and industry. The convergence of new technology platforms (e.g., induced pluripotent stem cells, CRISPR-Cas9 gene editing, 3D biology, advanced imaging) with other disciplines such as cheminformatics, machine learning, and artificial intelligence have led to an exciting renaissance of PDD. This meeting will bring together researchers performing or interested in PDD from across academia & industry. Although modern advances in PDD span both academic and industry sectors, there are few non-commercial drug discovery-focused meetings available for the community, and the Keystone Symposia program is a premiere forum for this topic.
This meeting will be held on May 22 - 25, 2022 in person or livestream attendance. Learn More HERE.
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This meeting will be held May 30 - June 3, 2022 at the Hilton New Orleans Riverside, New Orleans, Louisiana. Click HERE for more information.
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NIDDK Exocrine/Endocrine Pancreas Workshop
The goal of this 1.5-day workshop will be to gather clinical and basic science investigators who are interested in diseases of the exocrine and/or endocrine pancreas and in achieving an understanding of how the two compartments interact in disease. This workshop will provide an opportunity for investigators in exocrine diseases to come together with those studying islets in diabetes as a means to foster interdisciplinary discussion and identify areas for advancement. Learn more HERE
Please note that this meeting will now take place on June 29-30, 2022.
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THE SUGAR SCIENCE: STATE OF THE SCIENCE |
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The (sugar) science is hosting the final 2 of 6 State of the Science events to round out this series highlighting the voices of women scientists in T1D. A link to our repository of T1D scientist interviews is found HERE.
Additionally, we are putting together DChallenge 2022, with more information released April 1, 2022.
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IIDP Islet Isolation Centers Request for Proposals
The Integrated Islet Distribution Program (IIDP) is seeking experienced human islet isolation centers to apply for their Affiliated Islet Isolation Centers (IICs) Request for Proposals. Please share this opportunity with your islet isolation colleagues. Applications are due on March 31, 2022. Click HERE for more information.
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The Innovative Science Accelerator Program (ISAC) new funding program.
The ISAC Program supports truly innovative, disruptive, risky research to accelerate breakthrough discoveries.
ISAC provides:
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Funding for small high-risk/high reward projects via a streamlined process to support cutting-edge research and accelerate true innovation in scientific areas of interest to the Kidney-Urologic-Hematologic (KUH) research communities.
- Collaboration and Events for researchers and trainees to efficiently exchange ideas and resources to accelerate innovation.
Applications can be submitted to the ISAC web portal at any time. The review of submitted applications will occur three times a year and provide a quick turnaround from review to award.
- Application Final Submission: April 15, Aug 15, Dec 15
- Peer Review: May, Sept, Jan
- Notification of Award: June, Oct, Feb
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Helmsley Charitable Trust’s Type 1 Diabetes (T1D)
A goal of the Helmsley Charitable Trust’s (Helmsley) Type 1 Diabetes (T1D) Program is to support the discovery and development of interventions to prevent or delay the development of T1D. To address this, the Helmsley T1D Program is pleased to announce two funding opportunities to support:
- New efforts to understand relationships between the prenatal development period and initiation of islet autoimmunity.
IIIIIIIIILearn more HERE.
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New studies into understanding and therapeutically emulating examples where individuals are naturally protected from developing T1D. Learn More HERE.
Timeline for both opportunities:
Posted: February 1, 2022
Concept notes due: March 15, 2022
Full grant proposal due: June 1, 2022
Start date: November 1, 2022
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NIH FUNDING OPPORTUNITIES |
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RFA-DK-21-030: New Investigator Gateway Awards for Collaborative T1D Research (R03 Clinical Trial Not Allowed)
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Application due date: June 1, 2022 and March 20, 2023
- Foreign applications are not eligible
F31 PAR-19-378: Bioinformatics Interdisciplinary Predoctoral Fellowship in Diabetes, Endocrinology and Metabolic Diseases
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Application due date: Standard dates apply
- Foreign applications eligible
F32 PAR-19-379: Bioinformatics Interdisciplinary Postdoctoral Fellowship in Diabetes, Endocrinology and Metabolic Diseases
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Application due date: Standard dates apply
- Foreign applications eligible
PAR-20-140: Catalytic Tool and Technology Development in Kidney, Urologic, and Hematologic Diseases (R21 Clinical Trial Not Allowed)
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Application due date: Standard dates apply
- Foreign applications are eligible
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Below is a summary of the most recent job postings by category (Faculty, Research Staff/Admin, Postdoc). Visit the HIRN Website for a full listing for job opportunities.
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Program Director for Integrative Physiology of Human Diabetes
The National Institute of Diabetes and Digestive and Kidney Diseases is hiring a Program Director for Integrative Physiology of Human Diabetes. A scientist with strong managerial, communications and interpersonal skills, and experience in integrative physiology relevant to diabetes, is sought for the position of Program Director for Integrative Physiology in the Division of Diabetes, Endocrinology, and Metabolic Diseases (DDEMD) in the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), at the National Institutes of Health. Research to be managed by the Director of DDEMD’s Integrative Physiology program is supported through multiple mechanisms, including regular research grants and cooperative agreements. Activities to be pursued include planning, establishing, and overseeing a wide range of goal-directed initiatives to expedite and enhance translational, pre-clinical and clinical research in diabetes. Apply HERE.
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Program Officials
The National Institute of Diabetes and Digestive and Kidney Diseases is hiring program officials with expertise in translational research in any of the following four topic areas as they specifically relate to key questions in diabetes, endocrine or metabolic diseases:
· Integrative physiology of human diabetes, including physiology of counter-regulatory responses to hypoglycemia, mechanisms involved in regulation of peripheral metabolism, autonomic nervous system regulation of glucose and lipid metabolism, and basic and clinical studies investigating effects of bariatric surgery on diabetes and diabetes-related outcomes;
· Neuroscience of human behavior and behavior change, including brain and peripheral systems that impact the onset, severity or resolution of diabetes or obesity pathophysiology;
· Immune regulation and inflammation, including innate and adaptive immune mechanisms influencing peripheral insulin resistance in animal models and humans;
· Precision medicine in diabetes and obesity.
The mission of the Division of Diabetes, Endocrinology and Metabolic Diseases is to support broad-based research programs focused on both basic and clinical research in the areas of type 1 and type 2 diabetes and other metabolic diseases. Apply Here
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Staff Scientist
A staff scientist is sought to fill a position to work in the diabetes research and regenerative medicine laboratory of Dr. Jeffrey Millman at Washington University in St. Louis. The laboratory focuses on the generation insulin-producing pancreatic β cells for the study and treatment of diabetes. We have a wide diversity of projects involving stem cells differentiation, genetic engineering with CRISPR, disease modeling, transplantation into animal models of diabetes, biomedical engineering, bioinformatics, and single-cell sequencing technologies and has been very productive with publications in high impact journals. The ideal candidate would be able to provide high level support across multiple projects. Please send your CV, cover letter, and contact information with 3 references to
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Physician Scientist
The University of Chicago's Department of Medicine is searching for full-time physician scientist faculty members at any rank. Appointees will maintain a productive research program and provide patient care directly. Other responsibilities will include teaching and supervision of trainees and students. We are interested in applicants in any area of scientific investigation and clinical subspecialty, and especially welcome those whose research focus more broadly is in the areas of immunology/inflammation, diabetes, obesity, metabolism, sleep disorders, or cancer biology. Prior to the start of employment, qualified applicants must: 1) have a medical doctorate or equivalent, and 2) hold or be eligible for medical licensure in the State of Illinois. Please send your CV, cover letter, and contact information with 3 references to Dr. Mirmira.
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Scientific Writer
The University of Chicago's Department of Medicine's Section of Endocrinology, Diabetes and Metabolism in the Biological Sciences Division is searching for a scientific writer, whose primary activity will be providing communication and dissemination of scientific research under the direction of the principle investigator. The appointee will write, edit, proofread, and review scientific content including but not limited to scientific manuscripts, grant applications, and reports. Additionally, the appointee will prepare content for scientific conferences and presentations as well as maintain a social media presence for the lab. Additionally, the appointee will be required to maintain a high level of independent work and responsibility. Past experience in diabetes and/or metabolism research is preferable. Interested candidates should send their CV, a one-page summary of their past research and future research interests, and the contact information for 2-3 references directly to Dr. Mirmira.
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Project Manager
A multidisciplinary team at Vanderbilt seeks a Project Manager to coordinate multiple aspects of the Pancreatlas™ imaging resource, a public platform created to bring together imaging data from human pancreas samples to accelerate diabetes-related research. The candidate will oversee project operations, including maintaining documentation and organizational structures, leading regular meetings and establishing milestones, developing data visualization and metadata fields for new data types, identifying potential connections and collaborators, and creating written communications for conferences, meetings, or general publicity within the research community. The candidate will also provide biological expertise for data curation and publication. For more information and official job posting, contact Dr. Diane Saunders.
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Data Curator
The Powers & Brissova Research Group seeks a Data Curator to lead data and metadata curation for human pancreas and islet phenotyping projects. As a member of a multidisciplinary research team, the candidate will coordinate and maintain project timelines, assess and continually improve on best practices for local metadata/data storage and annotation, and assist group members with data analysis, visualization, and sharing. These responsibilities will include supporting the Pancreatlas™ imaging resource, a public platform created at Vanderbilt to bring together imaging data from human pancreas samples to accelerate diabetes-related research. The candidate will assist contributors with submitting and publishing imaging and other data types, including integrating existing metadata ontologies and identifying opportunities for cross-referencing with different scientific programs. The candidate will also use their knowledge of data structures to assist database developers in building a graph database and visualization tools connecting imaging and omic resources. For more information and official job posting, contact Dr. Marcela Brissova.
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Research Technician
A new Stem Cell and Genome Editing Core Facility situated within the Kieffer Research Group has an opportunity for a highly motivated and collaborative technician to support diverse regenerative medicine research initiatives. The candidate will assist with the day to-day operation of the Core, will generate human induced pluripotent cells (iPSCs), and will culture and differentiate human embryonic stem cells (ESCs) and iPSCs down pancreatic lineages. Please send your CV, cover letter, and contact information with 3 references to
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Postdoctoral Position
The University of Zurich and ETH Zurich is looking for a postdoctoral fellow to characterize the phenotypic and functional changes that occur in islets and their surrounding environment in the natural history of T1D. The project is embedded in an exciting multi-laboratory collaboration that will generate functional, single-cell genomics and imaging mass cytometry data from cultured pancreas slices. The selected candidate will use imaging mass cytometry (IMC) to analyze pancreas slices from human donors with T1D. Machine learning approaches and systems biology analyses will be used to integrate the different types of data and correlate phenotypic changes with functional measurements performed on the same slices. In this position you will work in a collaborative and interdisciplinary team to study immune cells and pancreatic islet and exocrine cells in human pancreas slices. You will develop novel single-cell approaches to integrate functional, genomics and imaging mass cytometry data. A highly motivated Ph.D. or M.D.-Ph.D. level researcher with a passion for science who would like to work in a collaborative multidisciplinary research environment that combines tissue biology, computational biology, systems biology and biomedicine. Applicants for the position should provide a brief statement of research interests, CV, and the names of three references to
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Postdoctoral Position
The Department of Molecular & Medical Genetics at Oregon Health & Science University (OHSU) in Portland, Oregon, is seeking an enthusiastic and highly motivated post-doctoral fellow to study adeno-associated virus (AAV) and its application for human gene therapy in the lab, led by Professor Hiroyuki Nakai, M.D., Ph.D. Specifically, the lab is looking for a post-doctoral researcher who can effectively lead several projects, including a multi-PI (MPI) NIH project " U01DK123608 (MPIs: Nakai, Grompe and Kay): Gene Therapy for Diabetes." We seek to develop clinically relevant novel AAV vectors and methods for in vivo regeneration of insulin-secreting beta cells in rhesus macaques and understand the mechanisms behind the technologies. Interested applicants are encouraged to send a cover letter and C.V. to Dr. Hiroyuki Nakai.
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Postdoctoral Position
Rutgers, the State University of New Jersey, is seeking a Postdoctoral Fellow for the Child Health Institute of New Jersey. The position is available in El Ouaamari’s laboratory to investigate the role of the peripheral neurons in the regulation of systemic energy homeostasis in the context of obesity and diabetes. Self-driven, creative, resourceful and independent candidates with a PhD in neuroscience or neurobiology are encouraged to apply. Prior postdoctoral experience in neuroscience or related fields is preferred. Successful applicants will develop a research project focused on understanding how peripheral neurons control glucose and lipid homeostasis—with the long-term goal of identifying high-value biological data that can be harnessed to design neuromodulation-based strategies to counter obesity and diabetes. The candidate must be skilled in using in vitro and in vivo techniques for manipulating and monitoring neuronal activity and should have strong records of productivity and achievement. Preference will be given to applicants who have experience in islet biology as well. The successful candidate will also contribute to the training of undergraduate and graduate students and work closely with the PI on preparation and submission of research/review articles and grants. Interested candidates should send their CV, a one-page summary of their past research and future research interests, and the contact information for 2-3 references directly to
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Postdoctoral Position
Post-Doctoral Fellowship position in the Kulkarni Lab at Joslin Diabetes Center, Harvard Medical School. One position is available immediately for a period of 3 years each. Applications are invited from individuals with a PhD or MD or MD PhD degrees. Candidates with expertise in Bioinformatics will be especially relevant. Prospective candidates should have expertise in handling large ‘omics’ databases and be willing to work closely with other Fellows in the lab to assist in analyses of biological data from diverse projects focused on Metabolism. These include but are not restricted to defining pathways and identifying mechanisms that regulate pancreatic (endocrine and exocrine) biology and inter-organ cross-talk in the overall maintenance of glucose homeostasis. Other projects include induced pluripotent stem cells, genetically engineered and humanized mouse models. Candidates will also be encouraged to develop their own research interests. Applicants for the position should provide a brief statement of research interests, CV, and the names of three references to Dr. Kulkarni.
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Postdoctoral Position
The Diabetes Institute at the University of Florida (UFDI) is recruiting up to two new Postdoctoral Research Associate positions. Our type 1 diabetes program recognized, at an international level, for outstanding research, training, and clinical care. It is well-funded by a series of individual, programmatic, and training level (T32, F, K) grants supported by numerous federal (NIH) and foundational agencies. Our research programs are broad in their scope, highly interdisciplinary, and translational. Faculty affiliated with the UFDI are engaged in innovative and cutting edge research in the areas of autoimmunity, genetics, metabolism, pathology, cell biology, microscopy, and imaging. Candidates should submit a curriculum vitae, NIH Biosketch/personal research statement (one-two pages), and three letters of recommendation. Three letters of reference should be sent directly to Dr. Todd Brusko.
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Postdoctoral Position
The Freyberg laboratory is offering Postdoctoral positions to study roles of dopamine in pancreatic hormone secretion and in diabetes. Candidates must have Ph.D. and/or M.D. degrees. Previous experience with molecular biology, mammalian cell and pancreatic islet culture, fluorescence microscopy is also preferred but not required, although candidates with experience in these skills are strongly encouraged to apply. Training in more advanced techniques is a key aim of the postdoctoral position; the biggest requirement is the enthusiasm and ambition of the candidate to make important contributions to our understanding of dopamine actions in metabolism. Interested candidates should send their CV, a one-page summary of their past research and future research interests, and the contact information for 2-3 references directly to Dr. Zachary Freyberg.
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Postdoctoral Position
A Postdoctoral research Opportunity In Translational Immunology Columbia Center for Translational Immunology, Columbia University Irving Medical Center, New York, NY. The lab of Megan Sykes, MD, is inviting highly motivated, creative and experienced individuals with a strong interest in innovative immunology research in transplantation tolerance with significant translational potential. Human immune systems from patients and other hematopoietic cell sources will be developed and analyzed in human immune system mouse models. These projects evolve from more than 25 years of experience in these models and benefit from a strong infrastructure and expertise within the laboratory. The work is supported by the extensive resources of the Columbia Center for Translational Immunology and affiliated centers, including CyTOF, full spectrum flowcytometry (Cytek Aurora), 10x genomics platform, humanized mouse core and human studies core. We work in close collaboration with computational biologists in the Department of Systems Biology. A strong background in immunology and technical experience are required. Must have a PhD and/or MD degree. Applicants should submit a CV, brief description of accomplishments and goals, and contact information of 3 references HERE.
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Postdoctoral Position
The laboratory of Dr. Leonardo Ferreira in the Department of Microbiology and Immunology and the Hollings Cancer Center at the Medical University of South Carolina is searching for a postdoctoral fellow to lead regulatory T cell (Treg) research projects in the lab. The objective of the Ferreira Lab is to design and develop engineered immune cell therapies for autoimmune disease and aging. The candidate must have a PhD in biology, immunology, or a related field, and have demonstrated quality publication of their work. Please send your CV, cover letter, and contact information with three references to
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Postdoctoral Position
A postdoctoral associate position is available at the Diabetes Research Institute of the University of Miami. The main lines of research in the Beta Cell Regeneration Lab revolve around the development of regenerative strategies for type 1 diabetes, including stem cell differentiation into insulin-producing β-cells and islet regeneration. In particular, our current research is focused on the induction of human pancreatic ductal BMP-responsive progenitor cells, which we have identified and characterized by lineage tracing (Klein et al., Diabetes, 2015; Qadir et al., Cell Reports, 2018); single-cell RNAseq and transplantation of sorted populations (Qadir et al., PNAS, 2020); and organotypic culture (human pancreatic slices) techniques (Qadir et al., Nature Comms, 2020). Our seminal contribution to the development of the latter has enabled for the first time the real-time monitoring of β-cell regeneration in an in vitro setting that resembles the native organ. Interested applicants are encouraged to send a letter/statement of interests, CV, and contact information for 2-3 references to Dr. Juan Dominguez-Bendala.
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Postdoctoral Position
Benaroya Research Institute’s Center for Interventional Immunology seeking outstanding clinical investigator for faculty position as well as post-doctorate candidates or research fellows interested in clinical/translational research in type 1 diabetes and/or autoimmunity. Please send your CV, cover letter, and contact information with 3 references to Dr. Carla Greenbaum.
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Postdoctoral Associate
The laboratory of Dr. Jeffrey Millman in the Division of Endocrinology, Metabolism, and Lipid Research at Washington University School of Medicine is searching for a postdoctoral associates to lead several new research projects in the lab. The objective of the Millman Lab is to generate and study stem cell-derived beta cells for use in diabetic disease modeling and cell therapy. The candidate must have a PhD in cell biology, biomedical engineering, or related fields and has demonstrated quality publication of their work. Please send your CV, cover letter, and contact information with 3 references to Dr. Jeffrey Millman.
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Postdoctoral Position
The Arthur Riggs Diabetes & Metabolism Research Institute at City of Hope is looking for a talented postdoctoral fellow. The collaborative laboratories of Dr. John Kaddis is seeking innovative postdoctoral candidates to conduct in-silico translational research in the field of type 1 diabetes (T1D). This individual will participate in one or more projects that examine the role of molecular, cellular, genetic, and epidemiological variation in T1D. This candidate will have an opportunity to work with specialists in the fields of immunology, diabetes, and data/computer science. Expertise in statistical methods for disease risk prediction and modeling, as well as clinical data, genome sequence, SNP array, “-omics”, and large-scale genetic association analysis is helpful. Experience with public databases/repositories is highly desired. Necessary skills include those from bioinformatics, computer/data science, mathematics, software engineering, and computational biology. Please send your CV, cover letter, and contact information with 3 references to
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