April 2023| Center for Human Health and the Environment

Upcoming Events

April 7: Behavior and Neuroscience RIG Monthly Meeting 12:00pm Fox 304

Two trainees from Kurt Marsden's lab will be presenting about their work.

Melody Hancock (Bioinformatics PhD student): "Molecular pathways of CHD7 pathogenicity in a zebrafish CHARGE syndrome model using transcriptomic and proteomic analysis"

Sureni Sumathipala (Postdoctoral scholar): "Investigation of seizure susceptibility in Cyfip2-deficient zebrafish"

This is a great opportunity for trainees (and their mentors!) to receive feedback on their work in progress. Pizza will be provided.

April 17: Pulmonary RIG Symposium 2:00pm Tox 2104

Students and post-docs are encouraged to present their current research, to look for potential synergy and collaboration that can emerge. Refreshments will be provided.

Add the CHHE Google Calendar to your calendar to never miss an event or opportunity!

KUDOS

David Baltzegar was nominated for the 2023 ORI Awards for Excellence.

David was 1 of 12 employees nominated for the 2023 ORI Awards for Excellence. NC State University Award for Excellence is the most prestigious honor bestowed upon non faculty employees. The awards, given annually, recognize both SHRA and non faculty EHRA employees for accomplishments and contributions that go above and beyond normal job responsibilities. ORI nominates several outstanding employees each year.

Michael Cowley received a Workforce Diversity Supplement to his R01 from NIEHS, which will provide training and professional development opportunities for Vicmarie Marrero-Colon, a 3rd graduate student in the Toxicology Program.

Dr. Cowley also served on the Neurodevelopment, Synaptic Plasticity, and Neurodegeneration Fellowship Study Section as an ad hoc reviewer.

Coby Schal's resea rch on mutant cockroach sex was described in Bethany Brookshire's Ne w York Times a rticle titled Cockroach Sex Took a Strange Turn. Now More Mutations Have Emerged. Article

Nanette Nascone-Yoder was awarded two new grants.

R21 Fueling left-right asymmetry: The role of glycolysis in stomach curvature

The vertebrate left-right (LR) body axis specifies the proper anatomical position and morphology of multiple organs; thus, abnormal LR asymmetry, known as heterotaxy (HTX), can cause catastrophic syndromes of laterality-related birth defects

In this project, Nanette's lab will test the idea that the asymmetry of a specific organ, the stomach, is shaped by LR asymmetries in cellular metabolism. As such, this research may help resolve previously unexplained causes of HTX involving environmental disruptions of maternal and/or embryonic metabolic homeostasis.

R03 Metabolism and Malrotation from NICHD

This project investigates how atrazine, a ubiquitous herbicide, affects cellular metabolic processes (i.e., glycolysis and mitochondrial respiration), and regulates the developmental events that drive the elongation and rotation of the embryonic digestive tract. The results will provide new insight into the etiology of intestinal malrotation, a common birth defect with significant morbidity.

Jun Tsuji received the Alumni Association Outstanding Research Award and induction into the NC State Research Leadership Academy (RLA). The Research Leadership Academy (RLA),established in FY2016, is composed of the University’s most outstanding researchers and mentors from diverse fields; members are selected on their records of and active engagement in research and mentoring of faculty.

CHHE Spring 2023 Pilot Project Awardees

Title: Night Shift Work as an Environmental Carcinogen: Insights into Circadian Control of Epigenetic DNA Methylation Patterns in Cancer Hallmark Genes

Co-PI: Cathrine Hoyo, Dept. of Biological Sciences, NC State

Co-PI: Shobhan Gaddameedhi, Dept. of Biological Sciences, NC State

$50,000

Title: Earth Observation Data to Support Environmental Justice: Linking Non-permitted Poultry operations in North Carolina to Water Quality Impacts and Environmental Vulnerability Indice

Co-PI: Ayse Ercumen, Dept. of Forestry and Envrionmental Resources and Global WaSH Cluster, NC State

Co-PI: Mirela Tulbure, Dept. of Forestry and Environmental Resources and Center for Geospatial Analytics, College of Sciences, NC State

$50,000

Title: Using Sentinel Animals to Determine the Impact of Particulate Air Pollution of Asthma: A Phenotypic, Bioenergietic and Proteomic Analaysis of BAL Samples from Asthmatic Horses Living Outdoor

PI: Katie Sheats, Dept. of Clinical Sciences, NC State

$25,000

Title: Investigating the Role of Gut-liver Axis in Herbicide-induced Metabolic

PI: Xiaojing Liu, Dept. of Molecular and Structural Biochemistry, NC State

$25,000

Reminders

Cite and acknowledge NIH award support and the CHHE’s P30 grant in future publications and presentations by including this –

“Research reported in this publication was supported by the National Institute of Environmental Health Sciences of the National Institutes of Health under Award Number P30ES025128. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.”

Publications citing the Center grant in the acknowledgements of a manuscript and in the deposit of the manuscript in NIEMS are the currency for the P30 renewal!

CHHE Resources and Facilities Page for NIH Grants is available on the CHHE website .

PINS: When submitting your grants, be sure to select "Center for Human Health and the Environment" as a center in PINS.

Click here to check out CHHE Cited Publications!