Oxidative Stress and Its
Functional Consequences Measured
In Vivo
Using MRI
Professor, Anatomy & Cell Biology
Professor, Opthalmology
Wayne State University
Dr. Berkowitz' research focuses on transformational
in vivo
MRI evaluation of oxidative stress in emerging diseases such as neurodegeneration --
without
the need to inject a contrast agent to determine how and when antioxidant treatment efficacy is best achieved.
This new ability enables earlier evaluation of disease progression and anti-oxidant treatment efficacy than is currently possible with conventional methods. Most of Dr. Berkowitz' new assays of excessive free radical production and function are based on endogenous contrast mechanisms, which will greatly facilitate their translation into patients.