Biosensis Calretinin Antibodies

Illuminating Neural Pathways with Precision

The detection of calretinin has proven essential across various areas of neuroscience research. Primarily expressed in cerebellar granular cells and their parallel fibers but also in specific interneuron populations in the cortex, calretinin aids in studying neuronal differentiation and maturation in neurodevelopment. Identifying calretinin-positive neurons elucidates neural circuitry, particularly in the hippocampus and cortex. Its role in modulating calcium signaling is pivotal for research into synaptic plasticity. Calretinin levels are also studied in neurodegenerative diseases like Alzheimer's, providing insights into neuronal vulnerability and resilience. Additionally, calretinin-positive interneurons are a focus of epilepsy research because of their implications in seizure dynamics. Though primarily associated with interneurons, calretinin expression is also found in some sensory neurons, projection neurons, and specialized glial cells such as OPL microglia.

Calretinin Antibodies: Promoting Accuracy and Consistency

Biosensis offers a collection of anti-calretinin antibodies from various hosts, including a mouse monoclonal, two rabbit-hosted polyclonals, and an excellent chicken-hosted anti-calretinin antibody. They have been specifically selected not to react with the related calcium-binding proteins calbindin or parvalbumin and operate across all common applications from Western Blot to immunohistochemistry, including paraffin-embedded sections.

Mouse Monoclonal Antibody (M-1799-100)

Rat cerebellum stained with mouse anti-calretinin (M-1799-100, green) and chicken anti-calbindin

(C-1798-50, red) by Immunohistochemistry. 

Rabbit Polyclonal Antibody (R-1800-50)

Rat cerebellum stained with rabbit anti-calretinin

(R-1800-50, red) and mouse anti-calbindin

(M-1797-100, green) by Immunohistochemistry. 

Chicken Ployclonal Antibody (C-1801-50)

Staining of rat hippocampus with chicken anti-calretinin (C-1801-50, green) and mouse anti-parvalbumin (M-1813-100, red)

by Immunohistochemistry.

Rabbit Polyclonal Antibody (R-1042-100)

Immunohistochemical staining with rabbit polyclonal antibody to human Calretinin (R-1042-100) in paraffin-embedded human mammary cancer sections.

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