August 04, 2022

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BioPharmGuy


Last week’s email struck a chord – lot of people fired of complimentary emails. We appreciate them all, but the guy who used the term 'hero' who was imagining eating Wendy’s fries while going through 600 resumes was the winner. 


Also, in last week's newsletter we provided a list of companies illegally selling honey with an extra special ingredient, and you people couldn't click that link fast enough. No doubt you did your research and made sure to never buy those adulterated products. Good work.


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Companies Added & Removed

25 companies added, 15 removed. Some weird company names this week - you could even write a news article about them. The facts:


Who:

Validation Professionals


What:

Differentiated Therapeutics


When:

Eleven Therapeutics


Where:

Aisa Pharma


How:

Find Therapeutics


Summary file available on our downloads page. (To all our competitors - you're welcome, you lazy bums)

Industry

Strange Thing

In 2018, Eleven Biotherapeutics changed their name to Sesen Bio. It’s easy to discover that fact by scanning our list of defunct companies. But there must be something with the number 11, because in spite of this history, a new group has taken the name Eleven Therapeutics.


Hopefully they’ll go by Elle Therapeutics for short.


Overexuberant PR

Three people spit in a cup and the press release merited a title with an exclamation point. Don’t get us wrong, a saliva test that was as reliable as the brain-swab Covid test we’ve been stuck with to date would be great, but does anyone really get exclamation point-excited about Covid testing breakthroughs anymore?


Team Diversity

Always refreshing to see a picture of a lab group that tells you they care about diversity. A2Bio shows this with their 14-person lab group featuring Asian women, black women, white women, women with glasses, women with long hair, women with gloves, women without gloves, shorter women, taller women, older women & younger women. Diversity!


Find Therapeutics 

This company doesn’t need to publish a mission statement – their name basically doubles as one. If their whole operation is this optimized, good things are ahead. 


Team Roast – Zoom Edition

Have we not tortured our employees enough these past two years with all this Zoom nonsense? Do we really need to immortalize them by using Zoom screenshots on the Team page? NO ONE looks good on Zoom. Shame on you, Aarvik!


Stick to Crypto

Biotech is a fiendishly difficult place for outsiders to penetrate and succeed without extensive training. So when we hear of a 23 year-old with a Bachelors degree and industry experience consisting of an internship founding a company and getting $13M in investor cash, it sounds outlandish. But that’s the real story in Paris where Alexander Reeber has corralled that funding for his plant-based biomanufacturing company, Core Biogenesis. Would probably make more sense to refer to this source of funds as donors rather than investors. But who knows anymore - someone may acquire them for $100M before they ever create a product. #notmymoney

Find the story in your data.


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Health & Science

HIV Heart

The world’s first heart transplant between HIV positive individuals took place in the spring and the recipient is reportedly alive and well. While the supply of HIV+ hearts is undoubtedly low, at least they won’t go to waste now. 


HIV Stem Cells

On the topic, a 66 year-old man was cured of HIV thanks to a stem cell transplant. He was being treated for AML and the donor bone marrow cells harbored a CCR5 mutation known to be beneficial in preventing HIV.


This is the same gene targeted by the Chinese researcher who caused a furor by genetically modifying a human fetus in his mad science experiment. Sadly for that little girl, people with the CCR5  mutation seem to live shorter lives. Not so much a worry for this bone marrow transplant recipient.


HIV Gene Therapy

Good things come in threes. American Gene technologies has reached the point in their gene therapy HIV clinical trial where they will withdraw antiretroviral therapies in patients to see If the cure worked.


It’s pretty stunning how far we’ve come in the 40 years since HIV started spreading widely. Companies are successfully using technologies that were decades from even existing in the 80s. Biotech can be pretty amazing.


Great Vaccine Mystery

The only human virus to ever be eradicated was smallpox. By popular telling, a vaccine was created, disseminated, then after enough years that was that. Alas, the story is much more convoluted and strange. In fact, the virus that was primarily responsible for vaccinating humans was not even the smallpox virus. Not only that, no one knows what virus it was and it has effectively disappeared.


Simpler times, eh? Imagine a worldwide vaccination program occurring today where doctors eventually admitted they didn't even know what virus they were putting into people. And yet here we are in a smallpox-free world.

ETC.


Long ago in 2005, a writer by the name of Adam Wilson penned this implausibly still-online satire article about the concept of the iPod shuffle. Was it the same Adam Wilson responsible for creating this whole BioPharmGuy experience? Who can say for sure? (Yes, it was)


Bummer no one was willing to publish his piece on human cheese. But on that topic, what was once satirical has become very much real in the intervening years, though back in 2005 the joke was using milk to create the cheese, not skin bacteria from celebrities' armpits.  

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