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February 15, 2024

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Purchase Data

Promoted Listings

To Buy? Or To Build?

That is the question…


Do we stick with CDMOs or build internal manufacturing capacity? 

What are the costs and breakeven points under different scenarios? 

How do we weigh the risks and strategic considerations?  


It’s a big decision – get it right.  

jeff@valcapglo.com

BioPharmGuy

Fines for running onto the field at sporting events should be based on attendance.


Rate: $0.10 per attendee. 


So, at the Super Bowl it would have cost those clowns $8000 each. But at a local soccer game it would only be like $2.


This system would thus allow idiots to interrupt an event that fits their budget.


Thanks

Sometimes I discover a website that has clearly scraped BioPharmGuy, augmented the info slightly, and reposted it. 


Nothing brings me more joy than systematically identifying everything they’ve added, confirming the accuracy of it, then augmenting the BioPharmGuy directory. 


Thanks, jerks!


-BPG


January Funding Summary

Completely forgot about this, so apologies for the slight delay.


Last month we tracked $2.1B in funding at 56 private companies plus a trio of IPOs for $722M. A lot more IPOs being filed, so we may be turning a corner on that.


Biggest Round:

Avistone - $140M Series B


Cutest Round:

3Daughters - $2M Seed


Companies Added & Removed

59 companies added, 11 removed this week.


Best New Name:

Atommap


Worst New Name, Ever:

Trawsfynydd Therapeutics


You Will Be Missed:

Hap10 Bio


Excel summary file of adds/removals available free on our downloads page.

Industry

Novo/Catalent

In an interesting move for the biotech industry, Novo Holdings has purchased a major contract manufacturer, Catalent, then immediately sold some sites to Novo Nordisk, they of the Ozempic/Wegovy fame.


It appears Nordisk did not want to waste time bringing new production facilities online and instead decided buying them outright made more sense. Probably a wise decision on their part.


The question around the industry is, what happens when a major contract manufacturer gets bought out? What if Novo Nordisk’s rivals had existing contracts with Catalent? Clearly that would create a conflict of interest. 


The good news is there is a seemingly insatiable supply of companies entering the contract manufacturing space every year, so someone will fill the void eventually. But in the mean time there could be some pains.


Team Roast - Unnecessary Time Frame

Team pages exist partially to inform the visitor of how great executives are. Accomplishments are de rigueur and even some goals can be peppered in.


For example, the Chairman here wants to contribute to the development of Taiwanese medicines.


A laudable, if a bit generic goal. The thing we question is the need to indicate when he wants to achieve this.


Do they really have to point out his timeframe for doing so is "before his retirement"? Isn't that when ALL a person's work takes place?


By the way, BioPharmGuy is planning to get this newsletter sent out.


Time frame? Before you read it.


FORCED1

Always good to see a contrived acronym for a clinical trial. This latest one we discovered has been dubbed ELAINE.


How’d they tease out that pretty simple name? Easy:


Evaluating LAsofoxIfeNe in Esr1 mutations


Yeah, they took four letters from one word for that acronym-like beast.


They sort of get a pass since they forced this one in memory of a real person named Elaine. But a better option was sitting right in front of them:


Evaluating LAsofoxifene IN Esr1 mutations


Never OK

It’s annoying when the local school makes us submit something via a Google form. But there is NO way a biotech company should be utilizing one as their Contact page.


Unforgiveable!


Team Roast - Heavy Mettle

Tensentric boasts of having a team of rock stars and to prove it, they told them all to wear a band t-shirt for the team pics. Out of the roughly 80 folks, only the CFO and a handful of others declined. Impressive. The company was so stoked with their own idea they reposted a collage on Linkedin.


So, we've established that almost all these posers fall in line when authority asks them to do something, but do they have actual musical taste?


BioPharmGuy and friends successfully identified all but one shirt, and we have concluded the biggest determinant of whether a band would show up frequently was whether you can buy the shirt at Old Navy.


How else can you explain AC/DC being the most popular? That band has a very cool name and logo, but their catalog is pretty much one song repeated over and over. Impossible for 9% of people to love them this much. 


In total, we found 30 people chose the Old Navy bands - AC/DC, Beatles, Nirvana, Pink Floyd, Queen, Led Zeppelin & Rolling Stones.


On the other end, the following bands were previously unknown to BioPharmGuy: GreenSky Bluegrass, Infectious Grooves, & Toonmac.


(Note: we confirmed they're unknown for a reason)


Favorite deep cut band: Tokyo Police Club


Least effort: Guy who slapped on an "Eric Clapton" nametag


White Whale: This cloud shirt. We tried many avenues short of emailing the person directly (because that would be cheating). No luck. Any ideas?


Too In the Nose

A drug named VYD222 that is targeting the 'vid?


Much agreeable.


Tra...something

Trawsfynydd Therapeutics announced FDA approval of their clinical study, and no, we did not just have a seizure while typing the company's name - it’s really what they chose.


There is a place, and one place only, for the use of the Welsh language and that place is Wales.


Naming your Maryland-based company working on antivirals Trawsfynydd Therapeutics is professional negligence. Just ludicrous.


If they were really dedicated, wouldn't they have went with Trawsfynydd Therapiwteg?


Bunch of phonies.

Health & Science

Everyone's Guilty

Hey look, another article about how a big pharma company is making it more difficult for patients to get a drug they need.


At least that’s how the article starts. Then you get to the part where they indicate the problem is that health insurance companies will not make a simple swap of a branded product for a generic now that the branded one is out of production. 


But THEN you get to the real problem, which is indeed a cynical ploy by the huge drug company.


Long story short, due to a federal law that just went into effect, GSK would have had to sell Flovent to Medicaid at a loss. So, instead they discontinued Flovent, authorized one company to make a generic and will enjoy resulting profits.


The most cynical part is probably how the authorized generic was priced at a higher net cost than Flovent, and GSK claims they can't be blamed as they are not involved with pricing whatsoever.


Magic!


We’ve all come to believe generic means “cheaper”, but this goes to show you can't always believe it. Really you can't believe anything about this wreck of a healthcare industry anymore.


Summary of the parties in this story making life more difficult for asthmatic children: 


1) Big Pharma

2) Health Insurers

3) Generic Drug Company

4) Federal Government


That's a healthcare dysfunction bingo. USA! USA!


Earthpox

New pox just dropped in the viral hotbed known as Alaska.


Actually it was discovered in 2015, but only recently claimed its first victim, an immunocompromised man who passed away due to this newly popularized Alaskapox virus.


Back in the pre-pandemic times when viruses were named after locations, this moniker made at least a little sense. Marburg & Ebola are both viruses named after places of discovery.


But good grief, Alaska is not some village. It's bigger than all but 18 countries. Alaskapox is as location specific as Iranpox or Mongoliapox.


The silliest part is Alaska has three syllables and Fairbanks, the city where it first popped up, has only two syllables. So, picking the less informative name has made our lives harder.


They could have helped us out by naming it Northpox.


Anyways, they say this Alaskapox is not a major concern. But they would say that, wouldn't they...


Broken Trust

You’ve probably seen commercials for the plethora of mental health apps out there. What you probably haven’t seen is how those very companies are helping others to target you with ads based on the mental health info they have on you. 


For real.


One of them passed info on to Google such as “birth dates, insurance information, and the patient's responses to mental health self-evaluations through the app”.


Don’t worry – the feds are on the case and hitting them with fines for dozens of dollars


All is well, citizen – keep sending along your most personal information to the internet overlords.

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