August 17, 2023

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BioPharmGuy

Guy in a comment thread on Linkedin referred to me as the “Notorious BPG” and I gotta say, I loved it.


-BPG


Radiopharmaceuticals

A biotech publication created a list of 12 radiopharmaceutical companies and as always, we made sure we listed them. But when we went to check our radiopharmaceutical page on the website we realized it did not exist. Strange, because it was created a while ago.


Turns out we never added a link to our directory page. Oops. We list 61 right now – check 'em out.


Sponsor Openings

We had been totally booked up for 2023, but a future client fell through so the following 2023 newsletter spots are again available:


Sponsor – Nov 2, Nov 9, Nov 30, Dec 21

Featured Company – Nov 2, Nov 30


Please let us know if you're interested.


July Funding

Last month we tracked $1.1B in funding at 38 private companies plus four IPOs worth a total of $517M.


Biggest Round:

$152M for Sinotau Pharmaceutical


Cutest Round:

$1.25M for Wavely Diagnostics


Funding file available for download.


Companies Added & Removed

19 companies added, 11 removed this week.


Best New Name:

Adze Biotechnology


Worst New Name:

Georgiamune


You Will Be Missed, But We Feel Ok About It:

Solace Therapeutics


Excel summary file of adds/removals available on our downloads page.

Industry

New #1

Indiana’s pride and joy, Eli Lilly, is now the most valuable drug company in America. They edged out Johnson & Johnson for the top spot on the back of monster sales of Mounjaro and its potential as a weight loss drug down the line.


Hey, if you find yourself in Indianapolis, you can walk around Eli Lilly’s former house at Newfields and think about if he were alive today, that house would be about 20 times bigger.


Revivicor

The company who makes gene-edited pig kidneys with the hopes of getting them approved for human transplantation brought out the big PR guns yesterday with two simultaneous releases of case studies in which brain-dead patients had their kidneys replaced with the gene-edited pig variety.


In a seven-day case, the patient received pig kidneys, each with 10 modified genes, which ended up producing urine within four minutes and a total of 37 L in the first day. Whoa. Slow down, kidneys.


Slow down they did - urine production was down to about 5 L per day by the 7th day.


In the second, longer case, the patient's kidney has lasted 32 days, this time with only a single gene modification to the organ.


We are one step closer to kidney vending machines.


Solar System

Last week we demonstrated how far our Biopharm Universe had fallen. So, here's some better news - the solar system is healthy.


Starting at Blue Earth Diagnostics we pass MoonLake Immunotherapeutics and then encounter Venus MedTech, followed by the Mercurys (Bio, Biomed, Medical).


Continuing past Sun Pharmaceuticals we eventually reach Jupiter Neurosciences with its moons Ganymede & Io Biotech before grazing Saturn's moon Titan Pharmaceuticals.


As we pass into the abyss, Pluto Biosciences appears in front of us, letting us know all that's left beyond it is Voyager Therapeutics.


Foghorn Therapeutics

Sent out a press release to let the world know they hired a new CMO. What a snoozer.


You know, maybe it would have been a lot cooler if they had announced this using another method of communication like, oh we don’t know, a FOGHORN.


Impilo

New company launched this week and they’re calling themselves Impilo Therapeutics. This begs the question – did they check the BPG defunct page, see a company called Impilo Therapeutics was acquired in 2020 and still pick that name? Or did they simply ignore the most comprehensive resource of dead biotech company names? 


Ohhhh wait a minute, wait a minute, wait a minute. The CEO of the company that acquired Impilo was David Slack. The new CEO of this Impilo is David Slack. Here's the history:


-Impilo Therapeutics was acquired by CEND Therapeutics in 2020

-CEND Therapeutics merged with Caladrius Biosciences in Apr 2022, to become Lisata Therapeutics

-Lisata Therapeutics spun out some tech into the new Impilo Theraputics. 


The circle of biotech!


The question is, do we create a new entry for this reincarnation of Impilo, or assign it to the original entry. Decisions, decisions...


Name Fail: AgNovos Bioscience

Just learned about this company and almost skipped right over it because we don't list agricultural biotech companies. A company putting Ag before an upper-case letter always means they do agricultural stuff. Until today.


We wish them the best of luck in treating bone disease, despite the plant-centric name.

Health & Science

HeLa Lawsuits

If you thought last week’s settlement with Thermo Fisher closed the Henrietta Lacks exploitation saga, you have not been living in America very long.


Her estate has filed lawsuit #2, this time against Ultragenyx whose market cap is about 100x smaller than Thermo Fisher's. Ultrangenyx had posted a mention of its use of HeLa cells on their website which provided the estate all they needed.


Gonna go out on a limb and bet if any other company had a mention on their site, it’s already been scrubbed. But that’s what the Internet Archive is for, right?


Oh, it's also for discovering that BioPharmGuy listed a mere 1500 companies in 2010. (Had to start somewhere.)


Cuckoo Doctor Banned

A crazy anti-vax DO in Ohio who suggested Covid vaccines would magnetize people, just got her medical license pulled, but not for being a crazy anti-vaxxer. It was suspended because the medical board has been conducting an investigation and she has refused multiple times to answer questions.


Her (also) anti-vaxx lawyer is making the argument that her rights are being violated.


We're not sure where in the constitution it says, “henceforth, each state must create a medical board and grant licenses to anyone who wants one regardless of dumb s**t they do”, but maybe it was in the preamble.


Do Not Pass Go

The Sackler family, who controlled Purdue Pharma, the primary drug company behind the opioid crisis, signed a far-reaching settlement back in March of 2022 in which they would buy absolution from their sins by way of $6B in cash.


However, last week the US Supreme Court revoked this get out of jail free card.


At issue is using the bankruptcy system to absolve an individual’s liability. You know, since the company declared bankruptcy, not the family.


(by the way, the family pulled billions…yes, billions from the company before it declared bankruptcy)


This settlement is privilege at its highest level. They were literally buying their way out of consequences. Most Americans would agree that condoning this concept is not worth the extra money that may be brought in by avoiding the mammoth legal battles that would come otherwise. 


Stay tuned for the next news, expected in December.


Bull Market

There's a new product for sale to help with climate change: Gene-edited bull semen.


The company behind this, Semex (seriously?), uses bulls who produce about 30% less methane via belching than standard cows. Considering methane is 25x as potent of a greenhouse gas as CO2, this could be a helpful innovation for those of us who enjoy Earth as it is.

ETC.

That's a Rap

Former biotech CEO and current GOP presidential hopeful, Vivek Ramaswamy dropped some of his mic skills at the Iowa State Fair. He lost himself with Eminen’s Lose Yourself to the amusement of dozens


He did a pretty good job, but is that really the best angle to take when courting Republicans in Iowa


This looked more like something you’d see on MTV’s Rock the Vote from back in the 90s when they were trying to get young people to go to the polls. The supreme irony here being Vivek has proposed disenfranchising 20 MILLION young Americans by rescinding their right to vote until they turn 25. A true political genius.


Hopefully Vivek snaps back to reality and quits this charade sooner rather than later.

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